DCUN1D4 and CEP135

		DCUN1D4	CEP135
Description		defective in cullin neddylation 1 domain containing 4	centrosomal protein 135
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus	Centrosome Centriole Cytosol
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Neddylation	Centriole Replication Centriole-centriole Cohesion Positive Regulation Of Non-motile Cilium Assembly Positive Regulation Of Establishment Of Protein Localization
Pathways		Neddylation	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Familial squamous cell lung carcinoma ( 29924316) Height ( 28552196)	Bone mineral density (hip) ( 30172743) Daytime sleep phenotypes ( 27126917) Femoral neck bone mineral density ( 30172743) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: CAND1 CEP135 CUL2 CUL3 CUL4A CUL4B UBE2M VAV2	7 interacting genes: CLOCK DCUN1D4 PIBF1 REST SMAD9 SPINK2 USP46
Entrez ID		23142	9662
HPRD ID		13791	11097
Ensembl ID		ENSG00000109184	ENSG00000174799
Uniprot IDs		B4DH26 Q92564	Q66GS9
PDB IDs		5V89	5FCN 5NG4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?