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VPS18

Description VPS18 core subunit of CORVET and HOPS complexes
Image No pdb structure
GO Annotations Cellular Component
  • Lysosome
  • Lysosomal Membrane
  • Endosome
  • Early Endosome
  • Late Endosome
  • Autophagosome
  • Actin Filament
  • AP-3 Adaptor Complex
  • Clathrin-coated Vesicle
  • HOPS Complex
  • Late Endosome Membrane
  • CORVET Complex
  • Presynapse
  • Glutamatergic Synapse
Molecular Function
  • Actin Binding
  • Protein Binding
  • Syntaxin Binding
  • Protein-macromolecule Adaptor Activity
  • Metal Ion Binding
  • Ubiquitin Protein Ligase Activity
Biological Process
  • Intracellular Protein Transport
  • Vesicle Docking Involved In Exocytosis
  • Autophagy
  • Endosome Organization
  • Vacuole Organization
  • Lysosome Organization
  • Endosome To Lysosome Transport
  • Protein Ubiquitination
  • Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
  • Viral Entry Into Host Cell
  • Organelle Fusion
  • Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS
  • Hemoglobin ( 32888494)
  • Malaria ( 31844061)
  • Refractive error ( 32231278)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes 22 interacting genes: AKTIP CLCN3 COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B RAB7A RILP SHANK3 STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID 57617
HPRD ID 09776
Ensembl ID ENSG00000104142
Uniprot IDs A0A024R9R3 Q9P253
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025