SHANK2 and DLGAP3

Number of citations of the paper that reports this interaction (PubMedID 10527873)
64

Data Source:
BioGRID (two hybrid)

		SHANK2	DLGAP3
Description		SH3 and multiple ankyrin repeat domains 2	DLG associated protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Cytosol Neurofilament Plasma Membrane Postsynaptic Density Apical Plasma Membrane Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Ciliary Membrane	Plasma Membrane Postsynaptic Density Neuromuscular Junction Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding SH3 Domain Binding Synaptic Receptor Adaptor Activity Ionotropic Glutamate Receptor Binding	Amyloid-beta Binding Protein Binding Molecular Adaptor Activity
	Biological Process	Synapse Assembly Learning Positive Regulation Of Cell Population Proliferation Adult Behavior Social Behavior Negative Regulation Of Hippo Signaling Long-term Synaptic Potentiation Long-term Synaptic Depression Vocalization Behavior	Signaling Regulation Of Postsynaptic Neurotransmitter Receptor Activity Modification Of Synaptic Structure
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference ( 28552196) Hodgkin's lymphoma ( 34216518) Kawasaki disease ( 33692975) Late-onset Alzheimer's disease ( 27770636) Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075) Urate levels in obese individuals ( 25811787)	Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence ( 28440896)
Interacting Genes		33 interacting genes: ACE2 ADGRB2 ADGRL1 ADGRL2 ANO1 ARHGAP12 ARHGEF7 BAIAP2 BANF1 CLCF1 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNAJC19 DNM1 DNM2 GMNN HOMER1 MCF2 ORC2 PEX3 PPFIA1 PPP3CA PRSS1 RAB6A RHOT1 RIPOR3 SHARPIN SLC9A3 SSTR2	15 interacting genes: DLG1 DLG2 DLG3 DLG4 DLGAP1 GOLGA2 KANK2 KRTAP1-3 KRTAP5-2 MAGEA6 MAGI2 PTK2 PTK2B SHANK2 SHANK3
Entrez ID		22941	58512
HPRD ID		04479	18935
Ensembl ID		ENSG00000162105	ENSG00000116544
Uniprot IDs		A0A590UJ45 A6NHU9 C0SPH0 Q9UPX8	O95886
PDB IDs
Enriched GO Terms of Interacting Partners?
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