TMEM229B and VSIR

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM229B	VSIR
Description		transmembrane protein 229B	V-set immunoregulatory receptor
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Enzyme Binding Identical Protein Binding Endopeptidase Activator Activity
	Biological Process		Positive Regulation Of Gene Expression Positive Regulation Of Endopeptidase Activity Positive Regulation Of Cell Migration Zymogen Activation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Regulatory T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Collagen Catabolic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Glomerular filtration rate in chronic kidney disease ( 26420894) Glycerophospholipid levels ( 26068415) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Obesity-related traits ( 23251661) Parkinson's disease ( 25064009 28892059) Refractive error ( 32231278) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		42 interacting genes: ACBD5 AQP6 ARL13B BIK CD53 CD79A CPLX4 CREB3L1 EBP ERGIC3 FAM209A FKBP7 GORAB GPX8 HSD17B13 ITGAM LHFPL5 MFF MFSD14B MGST3 MMGT1 MUC1 MYG1 NCR1 NEMP1 PANX1 PIGP PKMYT1 PVR REEP4 SEC22B SLC10A6 SLC39A2 SYT2 TLCD4 TMEM14B TMEM35A TMEM45B TMPRSS2 TSNARE1 VAPA VSIR	27 interacting genes: APOD ASGR1 ATP6V0C BMP10 C14orf180 CCL4L2 CLEC7A CLRN2 CNIH3 DOLK MS4A13 PLPP6 PLPPR2 PLSCR1 SLC35B1 SLC35B4 SMAD3 SMCO4 TMEM100 TMEM14C TMEM218 TMEM229B TMEM97 TNF TSPAN2 TSPO2 VAMP3
Entrez ID		161145	64115
HPRD ID		08157	15160
Ensembl ID		ENSG00000198133	ENSG00000107738
Uniprot IDs		A0A024R699 Q8NBD8	Q9H7M9
PDB IDs			6MVL 6OIL 6U6V
Enriched GO Terms of Interacting Partners?
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