TMEM229B and PKMYT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM229B	PKMYT1
Description		transmembrane protein 229B	protein kinase, membrane associated tyrosine/threonine 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Golgi Membrane Nucleus Nucleoplasm Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process		Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Phosphorylation Regulation Of Mitotic Nuclear Division Meiotic Cell Cycle
Pathways			Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition Cyclin A/B1/B2 associated events during G2/M transition G2/M DNA replication checkpoint
Drugs			Fostamatinib
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Glomerular filtration rate in chronic kidney disease ( 26420894) Glycerophospholipid levels ( 26068415) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Obesity-related traits ( 23251661) Parkinson's disease ( 25064009 28892059) Refractive error ( 32231278) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)	Metabolic syndrome ( 20694148)
Interacting Genes		42 interacting genes: ACBD5 AQP6 ARL13B BIK CD53 CD79A CPLX4 CREB3L1 EBP ERGIC3 FAM209A FKBP7 GORAB GPX8 HSD17B13 ITGAM LHFPL5 MFF MFSD14B MGST3 MMGT1 MUC1 MYG1 NCR1 NEMP1 PANX1 PIGP PKMYT1 PVR REEP4 SEC22B SLC10A6 SLC39A2 SYT2 TLCD4 TMEM14B TMEM35A TMEM45B TMPRSS2 TSNARE1 VAPA VSIR	24 interacting genes: ABHD16A BCL2 CCNB1 CD3E CD79A CDK1 CLDN8 ELOVL4 FATE1 LIME1 LRRC25 MAPK10 MAPK8 MFSD14B MFSD5 PIN1 PLK1 RETREG3 SLC10A1 SLC30A8 STEAP3 TMEM101 TMEM229B TMX2
Entrez ID		161145	9088
HPRD ID		08157	03920
Ensembl ID		ENSG00000198133	ENSG00000127564
Uniprot IDs		A0A024R699 Q8NBD8	Q0IJ49 Q99640
PDB IDs			3P1A 5VCV 5VCW 5VCX 5VCY 5VCZ 5VD0 5VD1 5VD3
Enriched GO Terms of Interacting Partners?
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