CLCN7 and PACS1

Number of citations of the paper that reports this interaction (PubMedID 15692563)
86

Data Source:
HPRD (in vitro)

		CLCN7	PACS1
Description		chloride voltage-gated channel 7	phosphofurin acidic cluster sorting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Golgi Apparatus Cytosol COPI-coated Vesicle
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity	Protein Binding Transmembrane Transporter Binding
	Biological Process	Response To PH Chloride Transmembrane Transport	Protein Localization To Golgi Apparatus Protein Localization To Plasma Membrane
Pathways		Stimuli-sensing channels	Nef mediated downregulation of MHC class I complex cell surface expression
Drugs
Diseases
GWAS		Acute anterior uveitis in ankylosing spondylitis ( 32492107) Refractive error ( 32231278)	Acne (severe) ( 24927181) Bipolar disorder ( 21926972 33263727 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		16 interacting genes: AQP7 CD53 CREB3 GDAP1 GET1 KCNN3 LHFPL5 LYVE1 MTDH OPRM1 OSTM1 PACS1 SLC38A7 SLC66A2 TLCD4 TMEM179B	20 interacting genes: AOPEP CABP4 CARNS1 CLCN7 CSNK2A1 FURIN GDI1 GGA3 IGF2R JUN KLC2 LAMA4 MCAM OTUB1 PKD2 PPP2CA PPP2CB SLC24A1 USP9Y VAMP4
Entrez ID		1186	55690
HPRD ID		04103	06320
Ensembl ID		ENSG00000103249	ENSG00000175115
Uniprot IDs		P51798	A0A024R5H6 Q6VY07
PDB IDs		7BXU 7CQ5 7CQ6 7CQ7 7JM7
Enriched GO Terms of Interacting Partners?
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