PACS1 and MCAM

		PACS1	MCAM
Description		phosphofurin acidic cluster sorting protein 1	melanoma cell adhesion molecule
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol COPI-coated Vesicle	Extracellular Region Extracellular Space Nucleus Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Transmembrane Transporter Binding
	Biological Process	Protein Localization To Golgi Apparatus Protein Localization To Plasma Membrane	Angiogenesis Glomerular Filtration Cell Adhesion Anatomical Structure Morphogenesis Positive Regulation Of Cell Migration Vascular Wound Healing
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 33263727 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006) Waist circumference adjusted for body mass index ( 34021172)	Plateletcrit ( 32888494)
Interacting Genes		20 interacting genes: AOPEP CABP4 CARNS1 CLCN7 CSNK2A1 FURIN GDI1 GGA3 IGF2R JUN KLC2 LAMA4 MCAM OTUB1 PKD2 PPP2CA PPP2CB SLC24A1 USP9Y VAMP4	6 interacting genes: ADRB2 ATF7IP FYN PACS1 PTK2B SHROOM1
Entrez ID		55690	4162
HPRD ID		06320	01120
Ensembl ID		ENSG00000175115	ENSG00000076706
Uniprot IDs		A0A024R5H6 Q6VY07	A0A024R3I5 P43121
PDB IDs			6LYN
Enriched GO Terms of Interacting Partners?
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