BIRC8 and UBE2G2

Number of citations of the paper that reports this interaction (PubMedID 19690564)
64

Data Source:
BioGRID (two hybrid)

		BIRC8	UBE2G2
Description		baculoviral IAP repeat containing 8	ubiquitin conjugating enzyme E2 G2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Spindle Microtubule	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Apoptotic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301)
Interacting Genes		14 interacting genes: CASP9 FAM107A MAGED1 TNPO2 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2K UBE2N UBE2V1 UBE2W	41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		112401	7327
HPRD ID		12525	04387
Ensembl ID		ENSG00000163098	ENSG00000184787
Uniprot IDs			P60604
PDB IDs			2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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