UBE2G2 and FARP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		UBE2G2	FARP2
Description		ubiquitin conjugating enzyme E2 G2	FERM, ARH/RhoGEF and pleckstrin domain protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Cytoplasm Cytosol Cytoskeleton
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	Guanyl-nucleotide Exchange Factor Activity Cytoskeletal Protein Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Cell Adhesion Neuron Remodeling Rac Protein Signal Transduction Hair Cycle Process Osteoclast Differentiation Actin Cytoskeleton Reorganization Regulation Of Integrin Activation Regulation Of Catalytic Activity Semaphorin-plexin Signaling Pathway Podosome Assembly
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion RAC1 GTPase cycle
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301)	Body size at age 10 ( 32376654) Cerebrospinal fluid immune biomarker levels ( 32066700) Chronic lymphocytic leukemia ( 28165464 23770605) Copper levels ( 26025379) Disability (impaired activities of daily living) ( 31707593) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 23535732) Sum eosinophil basophil counts ( 27863252) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549 32154731) Type 1 diabetes ( 34127860) Vitiligo ( 27723757)
Interacting Genes		41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	4 interacting genes: PDZK1 SRC UBE2G2 YWHAG
Entrez ID		7327	9855
HPRD ID		04387	16885
Ensembl ID		ENSG00000184787	ENSG00000006607
Uniprot IDs		P60604	O94887
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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