BIRC8 and TNPO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BIRC8	TNPO2
Description		baculoviral IAP repeat containing 8	transportin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Spindle Microtubule	Nucleus Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Apoptotic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS			Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		14 interacting genes: CASP9 FAM107A MAGED1 TNPO2 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2K UBE2N UBE2V1 UBE2W	53 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C12orf40 C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RAN RBM45 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 TRMT1 ZBTB32 ZC2HC1C
Entrez ID		112401	30000
HPRD ID		12525	04301
Ensembl ID		ENSG00000163098	ENSG00000105576
Uniprot IDs			A0A024R7F7 O14787 Q05D48 Q4LE60
PDB IDs
Enriched GO Terms of Interacting Partners?
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