CD3D and KCNA3

Number of citations of the paper that reports this interaction (PMID 12604782)
18

Data Source:
BioGRID (fluorescent resonance energy transfer)

		CD3D	KCNA3
Gene Name		CD3d molecule, delta (CD3-TCR complex)	potassium channel, voltage gated shaker related subfamily A, member 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Membrane Raft
	Molecular Function	Transcription Coactivator Activity Transmembrane Signaling Receptor Activity Protein Heterodimerization Activity	Voltage-gated Ion Channel Activity Delayed Rectifier Potassium Channel Activity Outward Rectifier Potassium Channel Activity
	Biological Process	Cell Surface Receptor Signaling Pathway T Cell Differentiation T Cell Costimulation Positive Thymic T Cell Selection Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Immune Response T Cell Receptor Signaling Pathway	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		TCR signaling Downstream TCR signaling Generation of second messenger molecules Translocation of ZAP-70 to Immunological synapse Costimulation by the CD28 family PD-1 signaling Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Phosphorylation of CD3 and TCR zeta chains Adaptive Immune System	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AP2M1 CANX CD247 CD3E CD3G CD8A CD8B HERPUD1 KCNA3 TRA TRB	6 interactors: BAX CD3D DLG1 DLG4 IL16 KCNA2
Entrez ID		915	3738
HPRD ID		01730	15937
Ensembl ID		ENSG00000167286	ENSG00000177272
Uniprot IDs		B0YIY4 P04234	P22001 Q6P2D3
PDB IDs		1XIW
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Immune System Process Regulation Of Immune System Process T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Signaling T Cell Costimulation Cell Communication Regulation Of Defense Response To Virus Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Regulation Of Immune Response T Cell Receptor Signaling Pathway Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Leukocyte Activation Single Organismal Cell-cell Adhesion Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Endocytosis Clathrin-mediated Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Positive Regulation Of Cell-cell Adhesion Regulation Of Calcium-mediated Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Cell Surface Receptor Signaling Pathway Regulation Of Lymphocyte Activation Cytotoxic T Cell Differentiation Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Signal Transduction Cell Adhesion Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Immune Response Viral Process Synaptic Transmission	Regulation Of Membrane Potential Receptor Localization To Synapse Regulation Of Ion Transport Protein Localization To Synapse Cortical Actin Cytoskeleton Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Receptor Clustering Protein Localization To Membrane Nucleotide Phosphorylation Lymphocyte Activation Regulation Of Ion Transmembrane Transport Locomotion Leukocyte Activation Single Organismal Cell-cell Adhesion Epithelial Cell Proliferation Movement Of Cell Or Subcellular Component Viral Process Release Of Matrix Enzymes From Mitochondria Positive Regulation Of Apoptotic DNA Fragmentation B Cell Receptor Apoptotic Signaling Pathway T Cell Homeostatic Proliferation Synaptic Transmission Chemotaxis Cell Activation Optic Nerve Structural Organization B Cell Negative Selection Retinal Cell Apoptotic Process Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Antigen Receptor-mediated Signaling Pathway Cellular Component Assembly Regulation Of Nitrogen Utilization Retinal Cell Programmed Cell Death Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Protein Insertion Into Mitochondrial Membrane Post-embryonic Camera-type Eye Morphogenesis Positive Regulation Of Protein Complex Assembly Membrane Organization System Development Establishment Or Maintenance Of Cell Polarity Cell Part Morphogenesis Immune System Process Regulation Of Behavior B Cell Homeostatic Proliferation
Tagcloud ?		aurkb bub1b ccnb1 cd247 cd3g cd8a cdc20 cdca8 cenpa cytoscape dihydroxyfluorane epstain generank hindering itgb5 itk kif2c lcp2 limma lymphoblasts mad2l1 nup37 pik3r3 plcg2 prkcq rpa3 softwares vav3 zap70
Tagcloud (Difference) ?		aurkb bub1b ccnb1 cd247 cd3g cd8a cdc20 cdca8 cenpa cytoscape dihydroxyfluorane epstain generank hindering itgb5 itk kif2c lcp2 limma lymphoblasts mad2l1 nup37 pik3r3 plcg2 prkcq rpa3 softwares vav3 zap70
Tagcloud (Intersection) ?