NMI and TUBA3C

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		NMI	TUBA3C
Gene Name		N-myc (and STAT) interactor	tubulin, alpha 3c
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytoplasm Microtubule
	Molecular Function	Transcription Cofactor Activity Protein Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Inflammatory Response JAK-STAT Cascade Regulation Of Nucleic Acid-templated Transcription	Protein Folding Microtubule-based Process Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization
Pathways			Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs			Epothilone D Epothilone B
Diseases
GWAS			Fasting insulin-related traits (interaction with BMI) ( 22581228)
Protein-Protein Interactions		44 interactors: BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CNKSR3 COPS7B CYP2E1 EMILIN1 GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MTMR6 MTMR9 MYC MYCN NECAP2 POMZP3 PSMA1 SCEL SFR1 SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 TRAF5 TRIP12 TUBA3C TUBA3E TXLNA TXLNB	11 interactors: DYNLL1 DYNLT1 FYN GRM7 MYC NMI PFDN5 PXN SIAH1 TUBG1 YWHAQ
Entrez ID		9111	7278
HPRD ID		04632	03958
Ensembl ID		ENSG00000123609
Uniprot IDs		Q13287 Q8WTW2	Q13748 Q1ZYQ1
PDB IDs
Enriched GO Terms of Interacting Partners?		JAK-STAT Cascade JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Positive Regulation Of Stem Cell Proliferation Regulation Of Cell Proliferation Response To Growth Hormone Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Regulation Of Stem Cell Proliferation Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Development Of Secondary Male Sexual Characteristics Cellular Response To Cytokine Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cytokine-mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Histone H3-K4 Methylation Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Response To Cytokine Regulation Of Apoptotic Process Creatinine Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Gene Expression Positive Regulation Of Metabolic Process Allantoin Metabolic Process Isoleucine Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Proliferation Gene Expression Heterocycle Metabolic Process Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway RNA Metabolic Process Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics	Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Metabolic Process Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Substantia Nigra Development Positive Regulation Of Signal Transduction Cell Cycle Multicellular Organismal Development Regulation Of Apoptotic Process Neural Nucleus Development Anatomical Structure Development Anatomical Structure Morphogenesis Positive Regulation Of Mitochondrion Organization Regulation Of Cell Death Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Regulation Of Organelle Organization Developmental Process Regulation Of Intracellular Signal Transduction Midbrain Development Apoptotic Process Programmed Cell Death System Development Regulation Of Mitochondrion Organization Regulation Of Cellular Localization Intracellular Signal Transduction Feeding Behavior Cell Cycle Process Fibroblast Apoptotic Process Cell Death Cell Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Death Cytoskeleton Organization Cell Projection Organization G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Viral Process Learning Cellular Response To Growth Factor Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Shape Response To Growth Factor
Tagcloud ?		augment augments bait cbp coactivator coil coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Difference) ?		augment augments bait cbp coactivator coil coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Intersection) ?