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NMI and IFI35
Number of citations of the paper that reports this interaction (PMID
10950963
)
6
Data Source:
HPRD
(in vivo, two hybrid)
NMI
IFI35
Gene Name
N-myc (and STAT) interactor
interferon-induced protein 35
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Nucleus
Cytosol
Molecular Function
Transcription Cofactor Activity
Protein Binding
Protein Binding
Biological Process
Transcription From RNA Polymerase II Promoter
Inflammatory Response
JAK-STAT Cascade
Regulation Of Nucleic Acid-templated Transcription
Cytokine-mediated Signaling Pathway
Type I Interferon Signaling Pathway
Pathways
Interferon Signaling
Cytokine Signaling in Immune system
Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions
44 interactors:
BRCA1
BRMS1
C1orf216
C9orf72
CDKN2A
CNKSR3
COPS7B
CYP2E1
EMILIN1
GCSH
GOLGA8EP
HDDC3
HGS
HHLA3
HOXC9
HSPA8
IFI35
KDM1A
LCA5L
LSM4
MAD2L1BP
MTMR6
MTMR9
MYC
MYCN
NECAP2
POMZP3
PSMA1
SCEL
SFR1
SNAPC5
SOX10
STAT1
STAT3
STAT4
STAT5A
STAT5B
STAT6
TRAF5
TRIP12
TUBA3C
TUBA3E
TXLNA
TXLNB
6 interactors:
BATF
CLEC4G
KDM1A
MAPK1
NMI
PLEKHO1
Entrez ID
9111
3430
HPRD ID
04632
02844
Ensembl ID
ENSG00000123609
ENSG00000068079
Uniprot IDs
Q13287
Q8WTW2
P80217
PDB IDs
Enriched GO Terms of Interacting Partners
?
JAK-STAT Cascade
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Growth Hormone Receptor Signaling Pathway
Cellular Response To Growth Hormone Stimulus
Positive Regulation Of Stem Cell Proliferation
Regulation Of Cell Proliferation
Response To Growth Hormone
Regulation Of Cell Death
Positive Regulation Of Transcription, DNA-templated
Regulation Of Stem Cell Proliferation
Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Development Of Secondary Male Sexual Characteristics
Cellular Response To Cytokine Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Cytokine-mediated Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Histone H3-K4 Methylation
Negative Regulation Of RNA Biosynthetic Process
RNA Biosynthetic Process
Response To Cytokine
Regulation Of Apoptotic Process
Creatinine Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Erythrocyte Differentiation
Negative Regulation Of Gene Expression
Positive Regulation Of Metabolic Process
Allantoin Metabolic Process
Isoleucine Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Cell Proliferation
Gene Expression
Heterocycle Metabolic Process
Taurine Metabolic Process
Positive Regulation Of Gamma-delta T Cell Differentiation
Positive Regulation Of Mesenchymal Cell Proliferation
Negative Regulation Of Erythrocyte Differentiation
Prolactin Signaling Pathway
RNA Metabolic Process
Regulation Of Mesenchymal Cell Proliferation
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Gamma-delta T Cell Activation
Development Of Secondary Female Sexual Characteristics
JAK-STAT Cascade
Transcription, DNA-templated
RNA Biosynthetic Process
Myeloid Leukocyte Differentiation
Regulation Of Primitive Erythrocyte Differentiation
MAPK Import Into Nucleus
RNA Metabolic Process
Response To Stress
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Golgi Inheritance
T-helper 2 Cell Differentiation
Myeloid Cell Differentiation
Defense Response
Caveolin-mediated Endocytosis
T-helper 17 Cell Lineage Commitment
Cytosine Metabolic Process
T-helper 17 Cell Differentiation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Leukocyte Differentiation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Regulation Of Golgi Organization
Histone H3-K4 Demethylation
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Positive Regulation Of Megakaryocyte Differentiation
Type 2 Immune Response
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Blood Coagulation
Intracellular Signal Transduction
Hemostasis
Positive Regulation Of Hormone Biosynthetic Process
Lymphoid Progenitor Cell Differentiation
Regulation Of Early Endosome To Late Endosome Transport
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Histone H3-K9 Methylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Hematopoietic Stem Cell Differentiation
T-helper Cell Lineage Commitment
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Gland Development
Tagcloud
?
augment
augments
bait
cbp
coactivator
coil
coiled
enhances
except
hybrid
ifngamma
instead
interactor
interacts
interestingly
intrinsic
lacks
myc
potentiate
recruitment
reveal
screen
stat
stat1
stat2
stat5
stat5b
stats
yeast
Tagcloud (Difference)
?
augment
augments
bait
cbp
coactivator
coil
coiled
enhances
except
hybrid
ifngamma
instead
interactor
interacts
interestingly
intrinsic
lacks
myc
potentiate
recruitment
reveal
screen
stat
stat1
stat2
stat5
stat5b
stats
yeast
Tagcloud (Intersection)
?