EIF2B3 and STC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF2B3	STC2
Gene Name		eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	stanniocalcin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex	Extracellular Space Endoplasmic Reticulum Golgi Apparatus Perinuclear Region Of Cytoplasm
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, Nucleic Acid Binding Nucleotidyltransferase Activity	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Translation Translational Initiation Response To Heat Response To Glucose Gene Expression Oligodendrocyte Development Negative Regulation Of Translational Initiation In Response To Stress Response To Peptide Hormone Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process Cellular Response To Stimulus	Cellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry
Pathways		Recycling of eIF2:GDP Translation Eukaryotic Translation Initiation Cap-dependent Translation Initiation
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		5 interactors: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2	11 interactors: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN
Entrez ID		8891	8614
HPRD ID		09379	04717
Ensembl ID		ENSG00000070785	ENSG00000113739
Uniprot IDs		Q9HA31 Q9NR50	O76061 Q6FHC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Response To Endoplasmic Reticulum Stress Male Germ Cell Proliferation Translational Initiation Regulation Of Translational Initiation In Response To Stress Regulation Of Translation In Response To Stress	Regulation Of Catalytic Activity Regulation Of Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Cellular Process Regulation Of Endopeptidase Activity DNA-templated Transcription, Elongation Regulation Of Peptidase Activity Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Follicle-stimulating Hormone Signaling Pathway Negative Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Translational Initiation In Response To Stress
Tagcloud ?		1090c 1980s 314a 318a 877c ataxia atrophy compiled deterioration dystonic genetics hemiparesis hereditary leukoencephalopathy list macrocephaly manifestation matter movements necropsy optic spain spasticity suffered vanishing vwm	alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin nell1 ovarian pappa pla2g4a pof premature sprague uterine vcd vinylcyclohexene visible
Tagcloud (Difference) ?		1090c 1980s 314a 318a 877c ataxia atrophy compiled deterioration dystonic genetics hemiparesis hereditary leukoencephalopathy list macrocephaly manifestation matter movements necropsy optic spain spasticity suffered vanishing vwm	alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin nell1 ovarian pappa pla2g4a pof premature sprague uterine vcd vinylcyclohexene visible
Tagcloud (Intersection) ?