STC2 and ARHGEF40

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STC2	ARHGEF40
Gene Name		stanniocalcin 2	Rho guanine nucleotide exchange factor (GEF) 40
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Golgi Apparatus Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	Rho Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Cellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry	Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		11 interactors: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN	6 interactors: APP MAPT MYCBP SPERT STC2 TAC1
Entrez ID		8614	55701
HPRD ID		04717	13335
Ensembl ID		ENSG00000113739	ENSG00000165801
Uniprot IDs		O76061 Q6FHC9	Q8TER5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Catalytic Activity Regulation Of Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Cellular Process Regulation Of Endopeptidase Activity DNA-templated Transcription, Elongation Regulation Of Peptidase Activity Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Follicle-stimulating Hormone Signaling Pathway Negative Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Translational Initiation In Response To Stress	Regulation Of Developmental Growth Reproduction Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Axon Cargo Transport Reproductive Process Mating Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Single-organism Behavior Metal Ion Homeostasis Cellular Chemical Homeostasis Associative Learning Developmental Cell Growth Ion Homeostasis Behavior Regulation Of Growth Regulation Of Multicellular Organism Growth Adult Locomotory Behavior Cellular Homeostasis Microtubule-based Transport Learning Cytoskeleton-dependent Intracellular Transport Sexual Reproduction Developmental Growth Involved In Morphogenesis Multicellular Organismal Reproductive Process Cell Growth Synaptic Growth At Neuromuscular Junction Positive Regulation Of Corticosterone Secretion Multicellular Organism Reproduction Chemical Homeostasis Adult Behavior Collateral Sprouting In Absence Of Injury Positive Regulation Of Cytoskeleton Organization Response To Abiotic Stimulus Locomotory Behavior Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Saliva Secretion Positive Regulation Of Synaptic Transmission, Cholinergic Regulation Of Corticosterone Secretion Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Learning Or Memory Axon Choice Point Recognition Regulation Of Saliva Secretion Regulation Of Synaptic Transmission, Cholinergic Developmental Growth Cognition Positive Regulation Of Cellular Component Biogenesis
Tagcloud ?		alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin nell1 ovarian pappa pla2g4a pof premature sprague uterine vcd vinylcyclohexene visible
Tagcloud (Difference) ?		alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin nell1 ovarian pappa pla2g4a pof premature sprague uterine vcd vinylcyclohexene visible
Tagcloud (Intersection) ?