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EIF2B3
Gene Name
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Eukaryotic Translation Initiation Factor 2B Complex
Molecular Function
Translation Initiation Factor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Translation Factor Activity, Nucleic Acid Binding
Nucleotidyltransferase Activity
Biological Process
Translation
Translational Initiation
Response To Heat
Response To Glucose
Gene Expression
Oligodendrocyte Development
Negative Regulation Of Translational Initiation In Response To Stress
Response To Peptide Hormone
Positive Regulation Of GTPase Activity
Cellular Protein Metabolic Process
Cellular Response To Stimulus
Pathways
Recycling of eIF2:GDP
Translation
Eukaryotic Translation Initiation
Cap-dependent Translation Initiation
Drugs
Diseases
GWAS
Protein-protein Interactions
5 interactors:
EIF2S1
EIF2S2
GOLM1
NDUFB8
STC2
Entrez ID
8891
HPRD ID
09379
Ensembl ID
ENSG00000070785
Uniprot IDs
Q9HA31
Q9NR50
PDB IDs
Enriched GO Terms of Interacting Partners
?
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Unfolded Protein
ER-nucleus Signaling Pathway
Cellular Response To Topologically Incorrect Protein
Response To Unfolded Protein
Response To Endoplasmic Reticulum Stress
Male Germ Cell Proliferation
Translational Initiation
Regulation Of Translational Initiation In Response To Stress
Regulation Of Translation In Response To Stress
Tagcloud
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1090c
1980s
314a
318a
877c
ataxia
atrophy
compiled
deterioration
dystonic
genetics
hemiparesis
hereditary
leukoencephalopathy
list
macrocephaly
manifestation
matter
movements
necropsy
optic
spain
spasticity
suffered
vanishing
vwm