BHLHE40 and NOC4L

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BHLHE40	NOC4L
Gene Name		basic helix-loop-helix family, member e40	nucleolar complex associated 4 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Golgi Apparatus	Nucleus Nucleolus Integral Component Of Membrane Noc4p-Nop14p Complex Nuclear Membrane Small-subunit Processome
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity BHLH Transcription Factor Binding MRF Binding Protein Heterodimerization Activity E-box Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Circadian Rhythm Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		49 interactors: AAMP AANAT AES APH1A ARNTL BHLHE41 BRD7 BTRC CALML3 CCNK CDPF1 CHD3 COX5B DAB1 EHHADH ENO1 FBLN1 FBXW11 GMCL1P1 HDAC1 HIVEP1 KRTAP23-1 LARP4 MAGED1 MYOD1 NAA50 NOC4L NUMBL PDE6G PLEKHB2 PRKAA1 RBFOX1 RBM23 RBPMS RHOBTB3 RHOJ SETDB1 SIN3A SMYD1 SOX15 STAT3 STK19 TOB2 TOLLIP TTC23 TXNL4B VAC14 VIM ZHX1	13 interactors: BHLHE40 DAZAP2 DNAJA3 IKZF1 KRT15 NECAB2 NT5C2 PLSCR1 PRSS23 SSSCA1 TSC22D4 USHBP1 VIM
Entrez ID		8553	79050
HPRD ID		16050	14543
Ensembl ID		ENSG00000134107	ENSG00000184967
Uniprot IDs		O14503 Q6IB83	Q9BVI4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Rhythmic Process RNA Metabolic Process Regulation Of Circadian Rhythm Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Gene Expression Circadian Rhythm Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Circadian Rhythm Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Histone Modification Chromatin Modification Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Circadian Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Protein Metabolic Process Developmental Process Chromosome Organization Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Transcription, DNA-templated Protein Acetylation Biosynthetic Process	Positive Regulation Of Neutrophil Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Activation Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process T Cell Differentiation Cell Activation Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Phosphatidylserine Biosynthetic Process Positive Regulation Of NK T Cell Differentiation Activation-induced Cell Death Of T Cells Bergmann Glial Cell Differentiation Positive Regulation Of T Cell Activation Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Granulocyte Differentiation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Skeletal Muscle Acetylcholine-gated Channel Clustering Lymphocyte Differentiation Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Phospholipid Scrambling Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Immune System Process Mitochondrial DNA Replication T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Heterocycle Metabolic Process Regulation Of T Cell Activation Adenosine Metabolic Process Apoptotic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cell Activation Lymph Node Development Regulation Of Gene Expression Programmed Cell Death T Cell Apoptotic Process Peyer's Patch Development Leukocyte Cell-cell Adhesion Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intermediate Filament Organization Homotypic Cell-cell Adhesion Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts
Tagcloud (Difference) ?		ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts
Tagcloud (Intersection) ?