SPSB1 and ATM

  • Number of citations of the paper that reports this interaction (PMID 18449195)
  • 54
  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology)

SPSB1

ATM

Gene Name splA/ryanodine receptor domain and SOCS box containing 1 ATM serine/threonine kinase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Dental caries ( 23064961)
  • Immune response to anthrax vaccine ( 22658931)
  • Response to tocilizumab in rheumatoid arthritis ( 22491018)
Protein-Protein Interactions 10 interactors: ATM DDX4 KDM1A MET NOS2 PAWR PRMT1 PRMT6 RASA1 SUV39H1 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1
Entrez ID 80176 472
HPRD ID 18106 06347
Ensembl ID ENSG00000171621 ENSG00000149311
Uniprot IDs Q96BD6 Q13315
PDB IDs 2JK9 3F2O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attributable  contributes  define  downregulation  emphasizes  engineered  genetically  identifies  implicating  mammary  mediator  met  neu  overexpressing  pharmacologic  positively  potentiation  preexisting  principal  principally  promoting  protect  recurrence  relapse  spontaneously  sufficient  turn  upregulated 
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
Tagcloud (Difference) ?
attributable  contributes  define  downregulation  emphasizes  engineered  genetically  identifies  implicating  mammary  mediator  met  neu  overexpressing  pharmacologic  positively  potentiation  preexisting  principal  principally  promoting  protect  recurrence  relapse  spontaneously  sufficient  turn  upregulated 
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
Tagcloud (Intersection) ?