TMF1 and RAB6A

Number of citations of the paper that reports this interaction (PMID 15128430)
17

Data Source:
HPRD (in vitro)

		TMF1	RAB6A
Gene Name		TATA element modulatory factor 1	RAB6A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Endoplasmic Reticulum Golgi Apparatus	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Cytoplasmic Vesicle Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Transcription Cofactor Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Acrosome Assembly Positive Regulation Of Cytokine Production Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Spermatid Nucleus Differentiation Negative Regulation Of Gene Expression Sperm Motility Luteinizing Hormone Secretion Leydig Cell Differentiation Defense Response To Bacterium Negative Regulation Of Apoptotic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Testosterone Secretion	Protein Targeting To Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule
Pathways			Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: AR FER GFI1B ITSN2 KAT2B NR3C1 RAB6A SMARCA4	20 interactors: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1
Entrez ID		7110	5870
HPRD ID		03081	01543
Ensembl ID		ENSG00000144747	ENSG00000175582
Uniprot IDs		P82094 Q6PII6	P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Chromatin Modification Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA-templated Transcription, Initiation Chromatin Organization Regulation Of Gluconeogenesis Histone H3 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Hormone Peptidyl-amino Acid Modification Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Integrin Biosynthetic Process Glucocorticoid Mediated Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Gland Development Steroid Hormone Mediated Signaling Pathway Regulation Of Glucose Metabolic Process Positive Regulation Of Transcription, DNA-templated Histone Acetylation Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Kit Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Diapedesis Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of NF-kappaB Transcription Factor Activity Internal Protein Amino Acid Acetylation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Hormone-mediated Signaling Pathway Protein Acetylation Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Integrin Biosynthetic Process Minus-end-directed Organelle Transport Along Microtubule Negative Regulation Of Glucocorticoid Mediated Signaling Pathway Peptidyl-cysteine Methylation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Gene Expression Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Cellular Biosynthetic Process	Protein Geranylgeranylation Protein Localization Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Prenylation Protein Transport Establishment Of Protein Localization Minus-end-directed Organelle Transport Along Microtubule Cellular Protein Localization Transport Retrograde Transport, Endosome To Golgi Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Vesicle-mediated Transport Microtubule-based Movement Positive Regulation Of Hydrolase Activity Microtubule-based Transport Protein Targeting To Golgi Cytoskeleton-dependent Intracellular Transport Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Protein Targeting Organelle Assembly Protein Localization To Golgi Apparatus Endosomal Transport Protein Localization To Organelle Regulation Of Proteinase Activated Receptor Activity Epidermal Growth Factor Catabolic Process Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Testosterone Secretion Positive Regulation Of Catalytic Activity Organelle Transport Along Microtubule Intra-Golgi Vesicle-mediated Transport Microtubule Anchoring Rab Protein Signal Transduction Regulation Of Catalytic Activity Luteinizing Hormone Secretion Negative Regulation Of Phospholipase C Activity Positive Regulation Of Androgen Secretion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Establishment Of Protein Localization To Organelle Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Phagosome-lysosome Fusion Phagosome Acidification Negative Regulation Of Protein Targeting To Membrane
Tagcloud ?			autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Difference) ?			autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Intersection) ?