TMF1 and ITSN2

Number of citations of the paper that reports this interaction (PMID 22558309)
5

Data Source:
BioGRID (two hybrid)

		TMF1	ITSN2
Gene Name		TATA element modulatory factor 1	intersectin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Endoplasmic Reticulum Golgi Apparatus	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Transcription Cofactor Activity Protein Binding	SH3/SH2 Adaptor Activity Rho Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding
	Biological Process	Acrosome Assembly Positive Regulation Of Cytokine Production Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Spermatid Nucleus Differentiation Negative Regulation Of Gene Expression Sperm Motility Luteinizing Hormone Secretion Leydig Cell Differentiation Defense Response To Bacterium Negative Regulation Of Apoptotic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Testosterone Secretion	Endocytosis Positive Regulation Of Signal Transduction Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS			Working memory ( 21107309)
Protein-Protein Interactions		8 interactors: AR FER GFI1B ITSN2 KAT2B NR3C1 RAB6A SMARCA4	75 interactors: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EPS15 EPS15L1 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREML GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1
Entrez ID		7110	50618
HPRD ID		03081	09193
Ensembl ID		ENSG00000144747	ENSG00000198399
Uniprot IDs		P82094 Q6PII6	A6H8W8 Q9NZM3
PDB IDs			1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Chromatin Modification Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA-templated Transcription, Initiation Chromatin Organization Regulation Of Gluconeogenesis Histone H3 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Hormone Peptidyl-amino Acid Modification Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Integrin Biosynthetic Process Glucocorticoid Mediated Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Gland Development Steroid Hormone Mediated Signaling Pathway Regulation Of Glucose Metabolic Process Positive Regulation Of Transcription, DNA-templated Histone Acetylation Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Kit Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Diapedesis Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of NF-kappaB Transcription Factor Activity Internal Protein Amino Acid Acetylation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Hormone-mediated Signaling Pathway Protein Acetylation Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Integrin Biosynthetic Process Minus-end-directed Organelle Transport Along Microtubule Negative Regulation Of Glucocorticoid Mediated Signaling Pathway Peptidyl-cysteine Methylation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Gene Expression Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Cellular Biosynthetic Process	Vesicle-mediated Transport Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cell Communication Signaling Cellular Response To Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Component Assembly Signal Transduction Synaptic Vesicle Transport Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Cell-cell Signaling Response To Stimulus Establishment Of Vesicle Localization Cell Surface Receptor Signaling Pathway Vesicle Localization Organelle Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Process Negative Regulation Of Membrane Tubulation Regulation Of Signaling Protein Complex Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Vesicle Organization Establishment Of Organelle Localization Positive Regulation Of Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-regulating Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Death Transport Apoptotic Process Cellular Localization Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Differentiation Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Establishment Of Localization In Cell Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud ?			abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates
Tagcloud (Difference) ?			abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates
Tagcloud (Intersection) ?