ACTC1 and ABLIM3

Number of citations of the paper that reports this interaction (PMID 15337165)
2

Data Source:
HPRD (in vivo, in vitro)

		ACTC1	ABLIM3
Gene Name		actin, alpha, cardiac muscle 1	actin binding LIM protein family, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Membrane Sarcomere I Band Actomyosin, Actin Portion Extracellular Vesicular Exosome Blood Microparticle	Stress Fiber Cytoplasm Lamellipodium
	Molecular Function	ATP Binding ATPase Activity Myosin Binding	Actin Binding Zinc Ion Binding
	Biological Process	Apoptotic Process Metabolic Process Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Response To Drug Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction	Transcription, DNA-templated Axon Guidance Lamellipodium Assembly Actin Cytoskeleton Organization Cilium Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Striated Muscle Contraction	Axon guidance DCC mediated attractive signaling Netrin-1 signaling
Drugs
Diseases
GWAS		Prostate cancer (gene x gene interaction) ( 22219177) Refractive error ( 20835239)
Protein-Protein Interactions		35 interactors: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FSCN1 GAPDH GC HSPB1 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 WAS WIPF1	5 interactors: ACTC1 BRCA1 CCDC33 IKZF3 SSX2IP
Entrez ID		70	22885
HPRD ID		00015	12411
Ensembl ID		ENSG00000159251	ENSG00000173210
Uniprot IDs		B3KPP5 P68032	O94929
PDB IDs			1UJS 2DJ7
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Actin Cytoskeleton Organization Cytoskeleton Organization Actin Filament Organization Organelle Organization Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Component Size Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Cellular Component Assembly Regulation Of Actin Filament-based Process Regulation Of Cellular Component Organization Actin Filament-based Movement Phagocytosis Blood Coagulation Fc Receptor Signaling Pathway Hemostasis Cellular Localization Actin Filament Bundle Assembly Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Regulation Of Actin Filament Polymerization Actin Polymerization Or Depolymerization Regulation Of Protein Complex Assembly Platelet Activation Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Cellular Component Movement Positive Regulation Of Cytoskeleton Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Sodium Ion Transmembrane Transport Wound Healing Positive Regulation Of Organelle Organization Vesicle-mediated Transport Endocytosis Nucleus Localization Negative Regulation Of Protein Complex Assembly Maintenance Of Protein Location In Cell Cell Activation Positive Regulation Of Wound Healing Maintenance Of Protein Location Immune Response-regulating Signaling Pathway Maintenance Of Location In Cell Response To Wounding Cell Projection Assembly	Centrosome Organization Microtubule Organizing Center Organization Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K9 Acetylation Cytoskeleton Organization Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Indole-3-methanol Regulation Of Apoptotic Process Negative Regulation Of Centriole Replication Intraciliary Transport Involved In Cilium Morphogenesis Dosage Compensation By Inactivation Of X Chromosome Skeletal Muscle Thin Filament Assembly Regulation Of Cell Death Protein K6-linked Ubiquitination Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Skeletal Myofibril Assembly Regulation Of Histone H3-K9 Acetylation Anatomical Structure Development Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Microtubule Cytoskeleton Organization Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Organelle Assembly Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Developmental Process Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Postreplication Repair Positive Regulation Of Protein Acetylation Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Cardiac Myofibril Assembly Regulation Of Gene Expression By Genetic Imprinting Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of B Cell Differentiation Genetic Imprinting Actin-myosin Filament Sliding
Tagcloud ?		accompany ach3 ach4 cardiac cardiomyocytes cardiomyogenic cd29 commitment cscs elusive fate hdac hdac1 hdac2 hypothesize indicative loci mark modifications mscs myh6 myl2 noticed possess sca stronger tnni3 tnnt2 trichostatin
Tagcloud (Difference) ?		accompany ach3 ach4 cardiac cardiomyocytes cardiomyogenic cd29 commitment cscs elusive fate hdac hdac1 hdac2 hypothesize indicative loci mark modifications mscs myh6 myl2 noticed possess sca stronger tnni3 tnnt2 trichostatin
Tagcloud (Intersection) ?