SPP1 and CEP162

Number of citations of the paper that reports this interaction (PMID 22779921)
1

Data Source:
BioGRID (two hybrid)

		SPP1	CEP162
Gene Name		secreted phosphoprotein 1	centrosomal protein 162kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Projection Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Centrosome Centriole Spindle Cytosol Axonemal Microtubule
	Molecular Function	Cytokine Activity Protein Binding Extracellular Matrix Binding	Protein Binding
	Biological Process	Osteoblast Differentiation Inflammatory Response Cell Adhesion Embryo Implantation Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Neutrophil Chemotaxis Biomineral Tissue Development Response To Vitamin D Positive Regulation Of Bone Resorption Decidualization Response To Steroid Hormone Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury	Organelle Organization Cilium Assembly
Pathways		Signaling by PDGF Integrin cell surface interactions Degradation of the extracellular matrix	Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Protein-Protein Interactions		88 interactors: ABCF3 ACP5 AFF4 AMOTL2 APOA1 ATP2A2 ATP5F1 BAG6 BRD3 C1RL C2orf50 CACNG4 CALM1 CC2D1B CD44 CEP162 CHD1 CISD2 CMTM3 COMMD1 COPS5 CSNK2A1 CSNK2A2 CTNNBL1 CYB5R3 DCX DNAJB1 DNTTIP2 DSEL EEF1A1 EIF3K EPAS1 F2 FTH1 GRIPAP1 HBA2 HMGN1 IGFBP5 ITGA5 ITGA9 ITGAV ITGB1 KCNIP1 LRRC4 MAP1A MAP1B MARCKS MEOX2 MMP3 MMP7 MPPED1 MRPL23 NACA NCKAP1 NCSTN PDLIM7 PEMT PEPD PLD3 PRKACB PRKCA PRKG1 RANBP9 RAPGEF2 RBBP6 RIMS4 RPL13 RPL15 RPL5 RPS13 SEC24C SGTA SLC39A6 SNAPIN SSB STAU1 STK39 TBC1D8 TMEM168 TMEM30A TPT1 TTC1 TUBB UBQLN4 USP42 USP8 ZNF638 ZNF804A	6 interactors: CPNE4 KDM1A PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		6696	22832
HPRD ID		01325	10796
Ensembl ID		ENSG00000118785	ENSG00000135315
Uniprot IDs		B7Z351 P10451 Q3LGB0	Q5TB80
PDB IDs		3CXD 3DSF
Enriched GO Terms of Interacting Partners?		Wound Healing Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Neuron Projection Development Response To Wounding Chemotaxis Locomotion Membrane Organization Cell Projection Organization Axon Development Neuron Development Developmental Process Regulation Of Body Fluid Levels Cellular Localization Extracellular Matrix Organization Regulation Of Proteasomal Protein Catabolic Process Extracellular Structure Organization Chemical Homeostasis Anatomical Structure Development Axon Guidance Axonogenesis System Development Leukocyte Migration Translational Initiation Viral Process Ion Homeostasis Regulation Of Cellular Process Nervous System Development Multicellular Organismal Development Cell Migration Neuron Differentiation Metal Ion Homeostasis Cell Morphogenesis Involved In Neuron Differentiation Translational Elongation Immune System Process Integrin-mediated Signaling Pathway Viral Life Cycle Anatomical Structure Morphogenesis Cell Motility Homeostatic Process Neuron Projection Morphogenesis Heterotypic Cell-cell Adhesion Response To Stress Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development Regulation Of Protein Metabolic Process	Histone Modification Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromatin Modification Peptidyl-arginine N-methylation Histone H4-R3 Methylation Chromatin Organization Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Regulation Of Hematopoietic Progenitor Cell Differentiation Chromosome Organization Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Primitive Erythrocyte Differentiation Histone Methylation Regulation Of Protein Binding Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein Methylation Regulation Of Myeloid Cell Differentiation Peptidyl-amino Acid Modification Negative Regulation Of Megakaryocyte Differentiation Regulation Of Binding Negative Regulation Of Collateral Sprouting Organelle Organization Cellular Protein Modification Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Negative Regulation Of Axon Regeneration Histone H3-K4 Demethylation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Differentiation Methylation Histone H2A Acetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Bone Resorption Granulocyte Differentiation Regulation Of Axon Regeneration Negative Regulation Of Histone Methylation In Utero Embryonic Development Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K4 Methylation
Tagcloud ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose
Tagcloud (Difference) ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose
Tagcloud (Intersection) ?