BLVRB and RPL31

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		BLVRB	RPL31
Gene Name		biliverdin reductase B	ribosomal protein L31
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome	Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Biliverdin Reductase Activity Riboflavin Reductase (NADPH) Activity	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding
	Biological Process	Porphyrin-containing Compound Metabolic Process Heme Catabolic Process Small Molecule Metabolic Process Oxidation-reduction Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Metabolism of porphyrins Heme degradation	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs		Riboflavin NADH Biliverdine Ix Alpha Riboflavin Monophosphate 2\'-Monophosphoadenosine 5\'-Diphosphoribose 7,8-dimethylalloxazine Mesobiliverdin Iv Alpha
Diseases
GWAS
Protein-Protein Interactions		3 interactors: HMOX1 ORM1 RPL31	8 interactors: APP BLVRB BRCA1 CACNA1A CRKL EWSR1 GPR20 IL7R
Entrez ID		645	6160
HPRD ID		02967	17994
Ensembl ID		ENSG00000090013	ENSG00000071082
Uniprot IDs		M0R192 P30043	B7Z4C8 B7Z4E3 P62899
PDB IDs		1HDO 1HE2 1HE3 1HE4 1HE5	3J3B
Enriched GO Terms of Interacting Partners?		Smooth Muscle Hyperplasia Negative Regulation Of Mast Cell Cytokine Production Smooth Muscle Adaptation Negative Regulation Of Mast Cell Degranulation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Negative Regulation Of Mast Cell Activation Involved In Immune Response Heme Catabolic Process Wound Healing Involved In Inflammatory Response Inflammatory Response Heme Oxidation Aromatic Compound Catabolic Process Cellular Response To Arsenic-containing Substance Negative Regulation Of Mast Cell Activation Positive Regulation Of Chemokine Biosynthetic Process Cellular Response To Iron Ion Cellular Response To Cadmium Ion Endothelial Cell Proliferation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Leukocyte Migration Low-density Lipoprotein Particle Clearance Regulation Of Mast Cell Degranulation Response To Arsenic-containing Substance Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Vasodilation Response To Iron Ion Negative Regulation Of Muscle Cell Apoptotic Process Regulation Of Mast Cell Activation Plasma Lipoprotein Particle Clearance Negative Regulation Of Exocytosis Regulation Of Regulated Secretory Pathway Response To Nicotine Acute-phase Response Cellular Response To Nutrient Heme Metabolic Process Positive Regulation Of Chemokine Production Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of DNA Binding Regulation Of Vasodilation Excretion Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Porphyrin-containing Compound Metabolic Process Regulation Of Muscle Cell Apoptotic Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Chemokine Production Response To Cadmium Ion Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Plasma Lipoprotein Particle Levels Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Immune System Process	Cell Growth Neuromuscular Process Controlling Balance Synapse Assembly Positive Regulation Of Histone H4-K20 Methylation Cerebellar Molecular Layer Development Positive Regulation Of Histone H4-K16 Acetylation Growth Adult Locomotory Behavior Vestibular Nucleus Development Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Interleukin-7-mediated Signaling Pathway Neuromuscular Process Dendrite Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Collateral Sprouting In Absence Of Injury Gamma-aminobutyric Acid Secretion Adult Behavior Synapse Organization Cell Surface Receptor Signaling Pathway Cellular Response To Indole-3-methanol Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Acetylcholine Secretion, Neurotransmission Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Centriole Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Rhythmic Synaptic Transmission Intracellular Receptor Signaling Pathway Signal Transduction Dosage Compensation By Inactivation Of X Chromosome Axon Choice Point Recognition Positive Regulation Of Cell Cycle Process Protein K6-linked Ubiquitination Heme Catabolic Process Locomotory Behavior Cellular Chloride Ion Homeostasis Regulation Of Histone H3-K9 Acetylation Calcium Ion-dependent Exocytosis Of Neurotransmitter Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Chloride Ion Homeostasis Neuron Remodeling Gamma-aminobutyric Acid Transport Signaling Parathyroid Gland Development
Tagcloud ?		auc benign biliverdin bvr characterisation cryosections discriminating discrimination discriminatory feasible frozen hplc maldi masses multicomponent nano overexpressed pca peaks prostatectomies prostatectomy proteomics reductase roc stromal tof turned validation z	abcc5 akt1 albeit behalf britain crnde drivers dynl11 exome harboured hotspot ireland john journal k700e ltd mucinous perturbation sf3b sf3b1 sons spliceosomal spliceostatin splicing tmem14c unselected uqcc uveal wiley
Tagcloud (Difference) ?		auc benign biliverdin bvr characterisation cryosections discriminating discrimination discriminatory feasible frozen hplc maldi masses multicomponent nano overexpressed pca peaks prostatectomies prostatectomy proteomics reductase roc stromal tof turned validation z	abcc5 akt1 albeit behalf britain crnde drivers dynl11 exome harboured hotspot ireland john journal k700e ltd mucinous perturbation sf3b sf3b1 sons spliceosomal spliceostatin splicing tmem14c unselected uqcc uveal wiley
Tagcloud (Intersection) ?