BLVRB and ORM1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		BLVRB	ORM1
Gene Name		biliverdin reductase B	orosomucoid 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Biliverdin Reductase Activity Riboflavin Reductase (NADPH) Activity	Protein Binding
	Biological Process	Porphyrin-containing Compound Metabolic Process Heme Catabolic Process Small Molecule Metabolic Process Oxidation-reduction Process	Regulation Of Immune System Process Transport Acute-phase Response Inflammatory Response
Pathways		Metabolism of porphyrins Heme degradation
Drugs		Riboflavin NADH Biliverdine Ix Alpha Riboflavin Monophosphate 2\'-Monophosphoadenosine 5\'-Diphosphoribose 7,8-dimethylalloxazine Mesobiliverdin Iv Alpha
Diseases
GWAS			End-stage coagulation ( 23381943) Tourette syndrome ( 22889924)
Protein-Protein Interactions		3 interactors: HMOX1 ORM1 RPL31	9 interactors: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63
Entrez ID		645	5004
HPRD ID		02967	00724
Ensembl ID		ENSG00000090013	ENSG00000229314
Uniprot IDs		M0R192 P30043	P02763
PDB IDs		1HDO 1HE2 1HE3 1HE4 1HE5	3KQ0
Enriched GO Terms of Interacting Partners?		Smooth Muscle Hyperplasia Negative Regulation Of Mast Cell Cytokine Production Smooth Muscle Adaptation Negative Regulation Of Mast Cell Degranulation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Negative Regulation Of Mast Cell Activation Involved In Immune Response Heme Catabolic Process Wound Healing Involved In Inflammatory Response Inflammatory Response Heme Oxidation Aromatic Compound Catabolic Process Cellular Response To Arsenic-containing Substance Negative Regulation Of Mast Cell Activation Positive Regulation Of Chemokine Biosynthetic Process Cellular Response To Iron Ion Cellular Response To Cadmium Ion Endothelial Cell Proliferation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Leukocyte Migration Low-density Lipoprotein Particle Clearance Regulation Of Mast Cell Degranulation Response To Arsenic-containing Substance Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Vasodilation Response To Iron Ion Negative Regulation Of Muscle Cell Apoptotic Process Regulation Of Mast Cell Activation Plasma Lipoprotein Particle Clearance Negative Regulation Of Exocytosis Regulation Of Regulated Secretory Pathway Response To Nicotine Acute-phase Response Cellular Response To Nutrient Heme Metabolic Process Positive Regulation Of Chemokine Production Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of DNA Binding Regulation Of Vasodilation Excretion Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Porphyrin-containing Compound Metabolic Process Regulation Of Muscle Cell Apoptotic Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Chemokine Production Response To Cadmium Ion Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Plasma Lipoprotein Particle Levels Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Immune System Process	Platelet Degranulation Cell Aging Negative Regulation Of Vascular Wound Healing Epidermal Cell Division Positive Regulation Of Leukotriene Production Involved In Inflammatory Response Ectoderm And Mesoderm Interaction Interaction With Host Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Maintenance Of Mitochondrion Location Regulation Of Body Fluid Levels Positive Regulation Of Behavior Regulation Of Smooth Muscle Cell-matrix Adhesion Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Epidermal Cell Division Chronological Cell Aging Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Regulation Of Vascular Wound Healing Female Genitalia Morphogenesis Cloacal Septation Urinary Bladder Development Regulation Of Behavior Platelet Activation Positive Regulation Of Fibroblast Apoptotic Process Prostatic Bud Formation Cloaca Development Glutamate Catabolic Process Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of Mesoderm Development Negative Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Keratinocyte Proliferation Negative Regulation Of Plasminogen Activation Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Heme Catabolic Process Polarized Epithelial Cell Differentiation Negative Regulation Of Apoptotic Process Glutamate Biosynthetic Process Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Programmed Cell Death Negative Regulation Of Cellular Senescence Lateral Sprouting From An Epithelium Replicative Cell Aging Negative Regulation Of Cell Death Negative Regulation Of Epidermal Cell Differentiation Negative Regulation Of Fibrinolysis Positive Regulation Of Monocyte Chemotaxis Sarcoplasmic Reticulum Calcium Ion Transport
Tagcloud ?		auc benign biliverdin bvr characterisation cryosections discriminating discrimination discriminatory feasible frozen hplc maldi masses multicomponent nano overexpressed pca peaks prostatectomies prostatectomy proteomics reductase roc stromal tof turned validation z	3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro ormdl3 peroxide reticulum scavenger sod spliced ssr1 superoxide transferase xbp1s
Tagcloud (Difference) ?		auc benign biliverdin bvr characterisation cryosections discriminating discrimination discriminatory feasible frozen hplc maldi masses multicomponent nano overexpressed pca peaks prostatectomies prostatectomy proteomics reductase roc stromal tof turned validation z	3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro ormdl3 peroxide reticulum scavenger sod spliced ssr1 superoxide transferase xbp1s
Tagcloud (Intersection) ?