RPL31 and EWSR1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPL31	EWSR1
Gene Name		ribosomal protein L31	EWS RNA-binding protein 1
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Gene Ontology Annotations	Cellular Component	Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		8 interactors: APP BLVRB BRCA1 CACNA1A CRKL EWSR1 GPR20 IL7R	159 interactors: ACTL6A AGT ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BTK C10orf12 C11orf16 C19orf57 CALM1 CCDC91 CD177 CDK12 CEACAM5 CETP CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DHX9 DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EP300 EPAS1 EPT1 ERCC5 FAM131C FASN FLI1 FUS FXR2 GNPDA1 GPBP1L1 HBP1 HDAC3 HERPUD1 HIST1H2BN HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383
Entrez ID		6160	2130
HPRD ID		17994	00592
Ensembl ID		ENSG00000071082	ENSG00000182944
Uniprot IDs		B7Z4C8 B7Z4E3 P62899	Q01844
PDB IDs		3J3B	2CPE
Enriched GO Terms of Interacting Partners?		Cell Growth Neuromuscular Process Controlling Balance Synapse Assembly Positive Regulation Of Histone H4-K20 Methylation Cerebellar Molecular Layer Development Positive Regulation Of Histone H4-K16 Acetylation Growth Adult Locomotory Behavior Vestibular Nucleus Development Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Interleukin-7-mediated Signaling Pathway Neuromuscular Process Dendrite Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Collateral Sprouting In Absence Of Injury Gamma-aminobutyric Acid Secretion Adult Behavior Synapse Organization Cell Surface Receptor Signaling Pathway Cellular Response To Indole-3-methanol Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Acetylcholine Secretion, Neurotransmission Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Centriole Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Rhythmic Synaptic Transmission Intracellular Receptor Signaling Pathway Signal Transduction Dosage Compensation By Inactivation Of X Chromosome Axon Choice Point Recognition Positive Regulation Of Cell Cycle Process Protein K6-linked Ubiquitination Heme Catabolic Process Locomotory Behavior Cellular Chloride Ion Homeostasis Regulation Of Histone H3-K9 Acetylation Calcium Ion-dependent Exocytosis Of Neurotransmitter Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Chloride Ion Homeostasis Neuron Remodeling Gamma-aminobutyric Acid Transport Signaling Parathyroid Gland Development	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Viral Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter RNA Processing Negative Regulation Of Gene Expression Cellular Response To Stress Regulation Of Establishment Of Protein Localization Negative Regulation Of Transcription, DNA-templated MRNA Metabolic Process MRNA Processing Apoptotic Process Regulation Of Intracellular Transport Response To Virus Programmed Cell Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Transport Immune System Process Regulation Of Protein Localization Cell Death Defense Response Death Regulation Of Cell Death
Tagcloud ?		abcc5 akt1 albeit behalf britain crnde drivers dynl11 exome harboured hotspot ireland john journal k700e ltd mucinous perturbation sf3b sf3b1 sons spliceosomal spliceostatin splicing tmem14c unselected uqcc uveal wiley	arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1
Tagcloud (Difference) ?		abcc5 akt1 albeit behalf britain crnde drivers dynl11 exome harboured hotspot ireland john journal k700e ltd mucinous perturbation sf3b sf3b1 sons spliceosomal spliceostatin splicing tmem14c unselected uqcc uveal wiley	arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1
Tagcloud (Intersection) ?