ORM1 and GLUD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ORM1	GLUD1
Gene Name		orosomucoid 1	glutamate dehydrogenase 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Vesicular Exosome Blood Microparticle	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Regulation Of Immune System Process Transport Acute-phase Response Inflammatory Response	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process Tricarboxylic Acid Metabolic Process
Pathways			Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives
Drugs			L-Glutamic Acid NADH Hexachlorophene Nicotinamide-Adenine-Dinucleotide Adenosine-5\'-Diphosphate Guanosine-5\'-Triphosphate
Diseases
GWAS		End-stage coagulation ( 23381943) Tourette syndrome ( 22889924)
Protein-Protein Interactions		9 interactors: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63	11 interactors: ASGR2 CRP DYNLL1 GOT2 HPX LSM1 NR4A1 ORM1 SEC62 STAT5A VTN
Entrez ID		5004	2746
HPRD ID		00724	11748
Ensembl ID		ENSG00000229314	ENSG00000148672
Uniprot IDs		P02763	B3KV55 E9KL48 P00367
PDB IDs		3KQ0	1L1F 1NR1
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Cell Aging Negative Regulation Of Vascular Wound Healing Epidermal Cell Division Positive Regulation Of Leukotriene Production Involved In Inflammatory Response Ectoderm And Mesoderm Interaction Interaction With Host Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Maintenance Of Mitochondrion Location Regulation Of Body Fluid Levels Positive Regulation Of Behavior Regulation Of Smooth Muscle Cell-matrix Adhesion Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Epidermal Cell Division Chronological Cell Aging Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Regulation Of Vascular Wound Healing Female Genitalia Morphogenesis Cloacal Septation Urinary Bladder Development Regulation Of Behavior Platelet Activation Positive Regulation Of Fibroblast Apoptotic Process Prostatic Bud Formation Cloaca Development Glutamate Catabolic Process Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of Mesoderm Development Negative Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Keratinocyte Proliferation Negative Regulation Of Plasminogen Activation Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Heme Catabolic Process Polarized Epithelial Cell Differentiation Negative Regulation Of Apoptotic Process Glutamate Biosynthetic Process Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Programmed Cell Death Negative Regulation Of Cellular Senescence Lateral Sprouting From An Epithelium Replicative Cell Aging Negative Regulation Of Cell Death Negative Regulation Of Epidermal Cell Differentiation Negative Regulation Of Fibrinolysis Positive Regulation Of Monocyte Chemotaxis Sarcoplasmic Reticulum Calcium Ion Transport	Regulation Of Immune System Process 2-oxoglutarate Metabolic Process Regulation Of Immune Response Oxaloacetate Metabolic Process Transport Acute-phase Response Endocytosis Regulation Of Humoral Immune Response Positive Regulation Of Mast Cell Differentiation Receptor-mediated Endocytosis Acute Inflammatory Response Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Regulation Of Mast Cell Differentiation Fumarate Metabolic Process Development Of Secondary Male Sexual Characteristics Immune System Process Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Hormone-mediated Signaling Pathway Response To Ethanol Negative Regulation Of Mast Cell Apoptotic Process L-kynurenine Metabolic Process Creatinine Metabolic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response Regulation Of Mast Cell Apoptotic Process Positive Regulation Of Mast Cell Proliferation Positive Regulation Of Immune Response Glutamate Catabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Vesicle-mediated Transport Positive Regulation Of Innate Immune Response Taurine Metabolic Process Aspartate Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Posttranslational Protein Targeting To Membrane Negative Regulation Of Vasodilation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Erythrocyte Differentiation Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Prolactin Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro ormdl3 peroxide reticulum scavenger sod spliced ssr1 superoxide transferase xbp1s	alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Difference) ?		3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro ormdl3 peroxide reticulum scavenger sod spliced ssr1 superoxide transferase xbp1s	alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Intersection) ?