SCTR and SNTA1

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		SCTR	SNTA1
Gene Name		secretin receptor	syntrophin, alpha 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Microtubule Plasma Membrane Integral Component Of Plasma Membrane	Intracellular Cytoplasm Cytoskeleton Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Sarcolemma Protein Complex Postsynaptic Membrane
	Molecular Function	Secretin Receptor Activity	Actin Binding Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway Digestion Excretion	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Glucagon-type ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs		Secretin
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ADCYAP1 CALM1 CPAMD8 CYFIP1 DNAL4 PRKAR2A PRKCA SCT SNTA1	72 interactors: ABCA1 ABCC4 ACTA2 ADAMTS6 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B BAI1 BAI2 BAI3 C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6
Entrez ID		6344	6640
HPRD ID		01628	03009
Ensembl ID		ENSG00000080293	ENSG00000101400
Uniprot IDs		P47872 Q8IV17	B4DX40 Q13424
PDB IDs
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Activation Of Phospholipase C Activity Regulation Of Adenylate Cyclase Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Phospholipase C Activity Response To Growth Factor Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Phospholipase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of Phospholipase Activity Regulation Of CAMP Biosynthetic Process Positive Regulation Of Lipase Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of CAMP Metabolic Process Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Energy Reserve Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Muscle Contraction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Protein Metabolic Process Regulation Of Rhodopsin Mediated Signaling Pathway Response To Fibroblast Growth Factor Rhodopsin Mediated Signaling Pathway Regulation Of Peptide Hormone Secretion Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Hormone Secretion Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Response To Light Stimulus Positive Regulation Of Protein Modification Process Intracellular Signal Transduction Cellular Response To Organic Substance	Cell-cell Signaling Synaptic Transmission Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Ion Transport Muscle System Process Muscle Contraction Regulation Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Metal Ion Transport Ion Transport Regulation Of Muscle Contraction Blood Circulation Negative Regulation Of Adrenergic Receptor Signaling Pathway Monovalent Inorganic Cation Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cation Transport Regulation Of Striated Muscle Contraction Cell Surface Receptor Signaling Pathway Cation Transmembrane Transport Transmembrane Transport Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Homeostasis Positive Regulation Of Cell Proliferation Ion Transmembrane Transport Potassium Ion Import Regulation Of Phosphorus Metabolic Process Behavior Response To Stimulus Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transport CGMP Metabolic Process Positive Regulation Of Ion Transport Response To Drug Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Body Fluid Levels Multicellular Organismal Response To Stress Response To Stress Cellular Response To Stimulus
Tagcloud ?		abolishes acts angii angiotensin axis coexpresses erralpha hyperosmolality hyperosmotic hypertonic hypothalamic hypothalamus importantly lamina mediate nr3b1 osmoregulation osmoregulatory paraventricular salt secretin stimulations terminalis upregulates upstream vasopressin vital vp	acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound
Tagcloud (Difference) ?		abolishes acts angii angiotensin axis coexpresses erralpha hyperosmolality hyperosmotic hypertonic hypothalamic hypothalamus importantly lamina mediate nr3b1 osmoregulation osmoregulatory paraventricular salt secretin stimulations terminalis upregulates upstream vasopressin vital vp	acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound
Tagcloud (Intersection) ?