SNTA1 and C3AR1

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		SNTA1	C3AR1
Gene Name		syntrophin, alpha 1	complement component 3a receptor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Sarcolemma Protein Complex Postsynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding	Phosphatidylinositol Phospholipase C Activity Complement Component C3a Receptor Activity G-protein Coupled Receptor Activity C3a Anaphylatoxin Receptor Activity
	Biological Process	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Circulation Metabolic Process Positive Regulation Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of Angiogenesis Positive Regulation Of Neutrophil Chemotaxis
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		72 interactors: ABCA1 ABCC4 ACTA2 ADAMTS6 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B BAI1 BAI2 BAI3 C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6	3 interactors: C3 C4A SNTA1
Entrez ID		6640	719
HPRD ID		03009	05581
Ensembl ID		ENSG00000101400	ENSG00000171860
Uniprot IDs		B4DX40 Q13424	A8K2H7 Q16581
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Ion Transport Muscle System Process Muscle Contraction Regulation Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Metal Ion Transport Ion Transport Regulation Of Muscle Contraction Blood Circulation Negative Regulation Of Adrenergic Receptor Signaling Pathway Monovalent Inorganic Cation Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cation Transport Regulation Of Striated Muscle Contraction Cell Surface Receptor Signaling Pathway Cation Transmembrane Transport Transmembrane Transport Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Homeostasis Positive Regulation Of Cell Proliferation Ion Transmembrane Transport Potassium Ion Import Regulation Of Phosphorus Metabolic Process Behavior Response To Stimulus Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transport CGMP Metabolic Process Positive Regulation Of Ion Transport Response To Drug Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Body Fluid Levels Multicellular Organismal Response To Stress Response To Stress Cellular Response To Stimulus	Positive Regulation Of Apoptotic Cell Clearance Regulation Of Apoptotic Cell Clearance Regulation Of Complement Activation Positive Regulation Of Phagocytosis Regulation Of Humoral Immune Response Regulation Of Phagocytosis Regulation Of Acute Inflammatory Response Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Endocytosis Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Regulation Of Vasoconstriction By Circulating Norepinephrine Protein Activation Cascade Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Regulation Of Endocytosis Positive Regulation Of Type IIa Hypersensitivity Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Negative Regulation Of Endopeptidase Activity Leukocyte Mediated Immunity Adaptive Immune Response Negative Regulation Of Peptidase Activity Regulation Of Inflammatory Response Positive Regulation Of Activation Of Membrane Attack Complex Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Cellular Metabolic Process Regulation Of Vesicle-mediated Transport Regulation Of Endopeptidase Activity Positive Regulation Of Hypersensitivity Regulation Of Protein Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Inflammatory Response Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Complement Activation, Alternative Pathway Positive Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Positive Regulation Of Humoral Immune Response Positive Regulation Of Immune Response Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Protein Processing Regulation Of Triglyceride Biosynthetic Process
Tagcloud ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	african chabaudi cope demonstration falciparum fcgr3b highlighted hosts implicate implicating interplay lrrc25 malaria mapped mounted noncoding plasmodium polygenic rad21 responders retn sco1 signature slc39a8 slc3a2 tapbp transcriptomes validated west
Tagcloud (Difference) ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	african chabaudi cope demonstration falciparum fcgr3b highlighted hosts implicate implicating interplay lrrc25 malaria mapped mounted noncoding plasmodium polygenic rad21 responders retn sco1 signature slc39a8 slc3a2 tapbp transcriptomes validated west
Tagcloud (Intersection) ?