SNTA1 and KCNJ10

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		SNTA1	KCNJ10
Gene Name		syntrophin, alpha 1	potassium channel, inwardly rectifying subfamily J, member 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Sarcolemma Protein Complex Postsynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Microvillus Basolateral Plasma Membrane Apical Plasma Membrane Astrocyte Projection
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding	Receptor Binding Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity Identical Protein Binding
	Biological Process	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport	Potassium Ion Transport Inflammatory Response Synaptic Transmission Visual Perception Adult Walking Behavior Response To Blue Light Potassium Ion Import Optic Nerve Development Central Nervous System Myelination Regulation Of Ion Transmembrane Transport Regulation Of Long-term Neuronal Synaptic Plasticity Protein Homotetramerization Response To Glucocorticoid Response To Mineralocorticoid Regulation Of Sensory Perception Of Pain L-glutamate Uptake Involved In Synaptic Transmission Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Membrane Hyperpolarization
Pathways			GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Potassium transport channels Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		72 interactors: ABCA1 ABCC4 ACTA2 ADAMTS6 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B BAI1 BAI2 BAI3 C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6	8 interactors: APP DLG1 DLG4 IL16 INADL KCNJ16 SIAH1 SNTA1
Entrez ID		6640	3766
HPRD ID		03009	03732
Ensembl ID		ENSG00000101400	ENSG00000177807
Uniprot IDs		B4DX40 Q13424	P78508
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Ion Transport Muscle System Process Muscle Contraction Regulation Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Metal Ion Transport Ion Transport Regulation Of Muscle Contraction Blood Circulation Negative Regulation Of Adrenergic Receptor Signaling Pathway Monovalent Inorganic Cation Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cation Transport Regulation Of Striated Muscle Contraction Cell Surface Receptor Signaling Pathway Cation Transmembrane Transport Transmembrane Transport Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Homeostasis Positive Regulation Of Cell Proliferation Ion Transmembrane Transport Potassium Ion Import Regulation Of Phosphorus Metabolic Process Behavior Response To Stimulus Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transport CGMP Metabolic Process Positive Regulation Of Ion Transport Response To Drug Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Body Fluid Levels Multicellular Organismal Response To Stress Response To Stress Cellular Response To Stimulus	Chemotaxis Receptor Localization To Synapse Axon Guidance Regulation Of Ion Transmembrane Transport Protein Localization To Synapse Axonogenesis Synapse Organization Locomotion Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Ion Transport Cortical Actin Cytoskeleton Organization Neuron Projection Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Tight Junction Assembly Response To External Stimulus Receptor Clustering Neuromuscular Junction Development Neuron Apoptotic Process Nucleotide Phosphorylation Neuron Development Neuron Death Regulation Of Sodium Ion Transport Cell Morphogenesis Apical Junction Assembly Neuromuscular Process Controlling Balance Synapse Assembly Neuron Differentiation Cell Projection Organization Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Receptor Activity Synaptic Growth At Neuromuscular Junction Cell-cell Junction Assembly Cell Recognition Synaptic Transmission Neuromuscular Process Learning Dendrite Development Collateral Sprouting In Absence Of Injury Generation Of Neurons Neurogenesis Collateral Sprouting
Tagcloud ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	abcc8 acacb cacna1a camk2d cdkal1 chi csmd1 disequilibrium exome glud1 gnas hnf1a hyperinsulinism kcnh6 nos2 notch2 pde4c pik3r3 probands ryr3 scn8a slc24a6 slc37a3 sulf1 tdt tll1 trpc5 trpv3
Tagcloud (Difference) ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	abcc8 acacb cacna1a camk2d cdkal1 chi csmd1 disequilibrium exome glud1 gnas hnf1a hyperinsulinism kcnh6 nos2 notch2 pde4c pik3r3 probands ryr3 scn8a slc24a6 slc37a3 sulf1 tdt tll1 trpc5 trpv3
Tagcloud (Intersection) ?