SCTR and CYFIP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SCTR	CYFIP1
Gene Name		secretin receptor	cytoplasmic FMR1 interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Microtubule Plasma Membrane Integral Component Of Plasma Membrane	Ruffle MRNA Cap Binding Complex Focal Adhesion Lamellipodium SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Secretin Receptor Activity	Protein Binding Protein Complex Binding Rac GTPase Binding Actin Filament Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway Digestion Excretion	Regulation Of Cell Shape Rac Protein Signal Transduction Lamellipodium Assembly Ruffle Organization Axon Extension Cognition Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Glucagon-type ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs		Secretin
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ADCYAP1 CALM1 CPAMD8 CYFIP1 DNAL4 PRKAR2A PRKCA SCT SNTA1	15 interactors: ACTA1 APBB1 EFHC2 EFTUD2 FMR1 FXR2 GAS7 GNB1 MEOX1 PPP1CC PRPF40A RAC1 RFX6 SCTR TCERG1
Entrez ID		6344	23191
HPRD ID		01628	05890
Ensembl ID		ENSG00000080293	ENSG00000068793
Uniprot IDs		P47872 Q8IV17	Q7L576
PDB IDs			3P8C
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Activation Of Phospholipase C Activity Regulation Of Adenylate Cyclase Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Phospholipase C Activity Response To Growth Factor Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Phospholipase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of Phospholipase Activity Regulation Of CAMP Biosynthetic Process Positive Regulation Of Lipase Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of CAMP Metabolic Process Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Energy Reserve Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Muscle Contraction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Protein Metabolic Process Regulation Of Rhodopsin Mediated Signaling Pathway Response To Fibroblast Growth Factor Rhodopsin Mediated Signaling Pathway Regulation Of Peptide Hormone Secretion Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Hormone Secretion Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Response To Light Stimulus Positive Regulation Of Protein Modification Process Intracellular Signal Transduction Cellular Response To Organic Substance	Response To Abiotic Stimulus Actin Filament Polymerization Pancreatic Epsilon Cell Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Pancreatic D Cell Differentiation Actin Filament Organization Response To Light Stimulus System Development Actin Polymerization Or Depolymerization Negative Regulation Of Translation Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Skeletal Muscle Fiber Adaptation Protein Polymerization Engulfment Of Apoptotic Cell Response To Radiation Tissue Development Multicellular Organismal Development Mast Cell Chemotaxis Sclerotome Development Regulation Of Cell Morphogenesis Regulation Of Gene Expression Anatomical Structure Development Response To External Stimulus Energy Reserve Metabolic Process Cell Cycle Arrest Positive Regulation Of DNA Metabolic Process Cytoskeleton Organization Somite Specification
Tagcloud ?		abolishes acts angii angiotensin axis coexpresses erralpha hyperosmolality hyperosmotic hypertonic hypothalamic hypothalamus importantly lamina mediate nr3b1 osmoregulation osmoregulatory paraventricular salt secretin stimulations terminalis upregulates upstream vasopressin vital vp	4e bdnf boncat cap depends eif4e eif4g encoded find fmrp gtp implicate latter mek mnk1 mnks neurotransmission neurotrophic obscure overlap partner phosphorylates plasticity repressor silac subset synthesis translational whose
Tagcloud (Difference) ?		abolishes acts angii angiotensin axis coexpresses erralpha hyperosmolality hyperosmotic hypertonic hypothalamic hypothalamus importantly lamina mediate nr3b1 osmoregulation osmoregulatory paraventricular salt secretin stimulations terminalis upregulates upstream vasopressin vital vp	4e bdnf boncat cap depends eif4e eif4g encoded find fmrp gtp implicate latter mek mnk1 mnks neurotransmission neurotrophic obscure overlap partner phosphorylates plasticity repressor silac subset synthesis translational whose
Tagcloud (Intersection) ?