EDA2R and CEBPE

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EDA2R	CEBPE
Gene Name		ectodysplasin A2 receptor	CCAAT/enhancer binding protein (C/EBP), epsilon
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane	Nucleoplasm
	Molecular Function	Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Epidermis Development Ectodermal Cell Differentiation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Transcription, DNA-templated Phagocytosis Defense Response Macrophage Differentiation Cytokine Biosynthetic Process Defense Response To Bacterium Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS		Male-pattern baldness ( 22032556)	Acute lymphoblastic leukemia (childhood) ( 23512250 19684604)
Protein-Protein Interactions		7 interactors: C1QB CASP8 CEBPE EDA FADD TRAF3 TRAF6	44 interactors: ALX4 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CCT7 CEBPA CEBPD CEBPG COPS3 CSNK1A1L DDIT3 DENND4A E2F1 EDA2R FOS FOSL1 GATA1 GPR22 GTF2A1L IL7 JUN KDM2B LDOC1 MED16 MLLT6 MYB NELFB PIAS1 POU2F1 PSAT1 RB1 SIPA1L1 SPI1 STAT6 TAF5L TBX2 TCEB2 UBE2I ZFP2 ZMYM2 ZNF384
Entrez ID		60401	1053
HPRD ID		02230	02852
Ensembl ID		ENSG00000131080	ENSG00000092067
Uniprot IDs		B2RBZ9 E7EUS4 Q9HAV5	Q15744
PDB IDs			3T92
Enriched GO Terms of Interacting Partners?		TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Immune System Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Immune Response TRAIL-activated Apoptotic Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Innate Immune Response Innate Immune Response Positive Regulation Of Myeloid Cell Differentiation Leukocyte Differentiation Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Myeloid Leukocyte Differentiation Myeloid Leukocyte Differentiation Positive Regulation Of Macrophage Differentiation Immune Response-regulating Signaling Pathway Negative Regulation Of Necroptotic Process Negative Regulation Of Necrotic Cell Death Regulation Of Necroptotic Process Regulation Of Immune System Process Macrophage Differentiation Tube Formation Regulation Of Myeloid Cell Differentiation Hemopoiesis Regulation Of Necrotic Cell Death Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Immune System Development Organ Development Response To Other Organism Response To Biotic Stimulus Myeloid Cell Differentiation Positive Regulation Of Intracellular Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Regulation Of T Cell Apoptotic Process Response To Lipopolysaccharide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Apoptotic Process	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Gene Expression Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Leukocyte Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Cellular Process Myeloid Cell Differentiation Hemopoiesis Myeloid Leukocyte Differentiation Cellular Metabolic Process Immune System Development Negative Regulation Of Cellular Metabolic Process Organ Development Dendritic Cell Differentiation Anatomical Structure Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity System Development Myeloid Dendritic Cell Differentiation Leukocyte Activation Myeloid Dendritic Cell Activation
Tagcloud ?		admixture africans await breed ce compositionally deflate edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs scmh1 slc24a5 sliding visualise	10months 12p absolutely aligned alive altogether apart arid5b associating bcp boy chance divergent etv6 girl gstm1 gstt1 haa ikzf1 leukocytosis microsatellite nqo1 predisposition ptprj relapsed runx1 sibs tp63 twinned
Tagcloud (Difference) ?		admixture africans await breed ce compositionally deflate edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs scmh1 slc24a5 sliding visualise	10months 12p absolutely aligned alive altogether apart arid5b associating bcp boy chance divergent etv6 girl gstm1 gstt1 haa ikzf1 leukocytosis microsatellite nqo1 predisposition ptprj relapsed runx1 sibs tp63 twinned
Tagcloud (Intersection) ?