EDA2R

Gene Name		ectodysplasin A2 receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding
	Biological Process	Epidermis Development Ectodermal Cell Differentiation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS		Male-pattern baldness ( 22032556)
Protein-protein Interactions		7 interactors: C1QB CASP8 CEBPE EDA FADD TRAF3 TRAF6
Entrez ID		60401
HPRD ID		02230
Ensembl ID		ENSG00000131080
Uniprot IDs		B2RBZ9 E7EUS4 Q9HAV5
PDB IDs
Enriched GO Terms of Interacting Partners?		TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Immune System Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Immune Response TRAIL-activated Apoptotic Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Innate Immune Response Innate Immune Response Positive Regulation Of Myeloid Cell Differentiation Leukocyte Differentiation Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Myeloid Leukocyte Differentiation Myeloid Leukocyte Differentiation Positive Regulation Of Macrophage Differentiation Immune Response-regulating Signaling Pathway Negative Regulation Of Necroptotic Process Negative Regulation Of Necrotic Cell Death Regulation Of Necroptotic Process Regulation Of Immune System Process Macrophage Differentiation Tube Formation Regulation Of Myeloid Cell Differentiation Hemopoiesis Regulation Of Necrotic Cell Death Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Immune System Development Organ Development Response To Other Organism Response To Biotic Stimulus Myeloid Cell Differentiation Positive Regulation Of Intracellular Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Regulation Of T Cell Apoptotic Process Response To Lipopolysaccharide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Apoptotic Process
Tagcloud ?		admixture africans await breed ce compositionally deflate edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs scmh1 slc24a5 sliding visualise