SPTBN4 and CENPU

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SPTBN4	CENPU
Gene Name		spectrin, beta, non-erythrocytic 4	centromere protein U
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Adherens Junction Spectrin Membrane Nuclear Matrix PML Body Node Of Ranvier Paranode Region Of Axon Neuronal Cell Body Axon Initial Segment Axon Hillock Extracellular Vesicular Exosome Cell Body Fiber	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Microtubule Organizing Center Cytosol
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Phospholipid Binding Phosphatase Binding Ankyrin Binding Spectrin Binding
	Biological Process	Regulation Of Sodium Ion Transport Cytoskeletal Anchoring At Plasma Membrane Axonogenesis Axon Guidance Sensory Perception Of Sound Adult Walking Behavior Fertilization Negative Regulation Of Heart Rate Vesicle-mediated Transport Transmission Of Nerve Impulse Central Nervous System Projection Neuron Axonogenesis Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Multicellular Organism Growth Clustering Of Voltage-gated Sodium Channels Actin Filament Capping Cardiac Conduction Establishment Of Protein Localization To Plasma Membrane	Mitotic Cell Cycle Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Viral Process CENP-A Containing Nucleosome Assembly Chordate Embryonic Development
Pathways		Interaction between L1 and Ankyrins Axon guidance L1CAM interactions NCAM signaling for neurite out-growth	Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ANK3 CDC37 CELSR3 CENPU DISC1 GADD45A GSK3B NEK2 PFDN1 PTPRN PTPRN2 RPS6KA6	17 interactors: EIF4G1 GIT1 LAMC1 MLF1 NDUFS2 NUP62 PGRMC1 PLK1 PLK2 PLK3 PLXNB2 ROBO2 SPTBN4 TFIP11 TUBB2B UPF2 XRCC6
Entrez ID		57731	79682
HPRD ID		09372	14722
Ensembl ID		ENSG00000160460	ENSG00000151725
Uniprot IDs		C9JY79 Q9H254	Q09GN2 Q71F23
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Organelle Organization Axon Development Cytoskeleton Organization Locomotion Regulation Of Cellular Process Telencephalon Development Centrosome Cycle Nervous System Development Regulation Of Protein Localization Movement Of Cell Or Subcellular Component Maintenance Of Protein Location In Plasma Membrane Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Neuron Projection Development Multicellular Organismal Development Cell Projection Morphogenesis Cellular Response To Mechanical Stimulus Generation Of Neurons Cell Part Morphogenesis Anatomical Structure Development Axon Guidance Neurogenesis Negative Regulation Of Phosphorylation Neuron Development Signal Transduction In Response To DNA Damage Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Cell Communication By Electrical Coupling Negative Regulation Of Delayed Rectifier Potassium Channel Activity Superior Temporal Gyrus Development Dense Core Granule Maturation Canonical Wnt Signaling Pathway Central Nervous System Development Signal Transduction Centrosome Organization Negative Regulation Of Binding Microtubule Cytoskeleton Organization Forebrain Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Cycle Process Cell Morphogenesis Microtubule Organizing Center Organization Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Regulation Of Centriole-centriole Cohesion Developmental Process Protein Localization Neuron Differentiation Signaling Cell Projection Organization	Generation Of Neurons Neurogenesis System Development Developmental Process Axon Guidance Nervous System Development Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Cell Differentiation Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Locomotion Positive Regulation Of Cellular Protein Catabolic Process Neuron Projection Development Mitotic Cell Cycle Checkpoint Endomembrane System Organization Regulation Of Cellular Protein Metabolic Process Cell Projection Morphogenesis Negative Regulation Of Cell Cycle Cell Part Morphogenesis Mitotic Nuclear Envelope Disassembly Regulation Of Cell Cycle Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Movement Of Cell Or Subcellular Component Nuclear Envelope Disassembly Neuron Development Regulation Of Protein Metabolic Process Response To Stimulus Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Cell Cycle Process Cell Morphogenesis Regulation Of Cell Division Spliceosomal Complex Disassembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cytokinesis Neuron Differentiation Cell Projection Organization Nuclear Envelope Organization
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