CENPU and MLF1

Number of citations of the paper that reports this interaction (PMID 15116101)
13

Data Source:
HPRD (in vitro, two hybrid)

		CENPU	MLF1
Gene Name		centromere protein U	myeloid leukemia factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Microtubule Organizing Center Cytosol	Nucleus Nucleoplasm Cytoplasm
	Molecular Function		DNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Viral Process CENP-A Containing Nucleosome Assembly Chordate Embryonic Development	Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Cell Cycle Arrest
Pathways		Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: EIF4G1 GIT1 LAMC1 MLF1 NDUFS2 NUP62 PGRMC1 PLK1 PLK2 PLK3 PLXNB2 ROBO2 SPTBN4 TFIP11 TUBB2B UPF2 XRCC6	6 interactors: CENPU COPS3 GRIK5 MAGEA11 NRBP1 YWHAZ
Entrez ID		79682	4291
HPRD ID		14722	03239
Ensembl ID		ENSG00000151725	ENSG00000178053
Uniprot IDs		Q09GN2 Q71F23	B2RD48 P58340 Q2TLE4 Q5HYH4
PDB IDs			3UAL 3UBW
Enriched GO Terms of Interacting Partners?		Generation Of Neurons Neurogenesis System Development Developmental Process Axon Guidance Nervous System Development Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Cell Differentiation Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Locomotion Positive Regulation Of Cellular Protein Catabolic Process Neuron Projection Development Mitotic Cell Cycle Checkpoint Endomembrane System Organization Regulation Of Cellular Protein Metabolic Process Cell Projection Morphogenesis Negative Regulation Of Cell Cycle Cell Part Morphogenesis Mitotic Nuclear Envelope Disassembly Regulation Of Cell Cycle Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Movement Of Cell Or Subcellular Component Nuclear Envelope Disassembly Neuron Development Regulation Of Protein Metabolic Process Response To Stimulus Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Cell Cycle Process Cell Morphogenesis Regulation Of Cell Division Spliceosomal Complex Disassembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cytokinesis Neuron Differentiation Cell Projection Organization Nuclear Envelope Organization	Golgi Reassembly Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Histamine Secretion By Mast Cell Establishment Of Golgi Localization Golgi Inheritance Cullin Deneddylation Histamine Secretion Protein Retention In ER Lumen Protein Deneddylation Maintenance Of Protein Localization In Endoplasmic Reticulum Histamine Transport Golgi Localization Mast Cell Degranulation Protein Localization To Organelle Production Of Molecular Mediator Involved In Inflammatory Response Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Mast Cell Mediated Immunity Establishment Of Localization In Cell CENP-A Containing Nucleosome Assembly Lysosome Localization Positive Regulation Of Apoptotic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Programmed Cell Death Mast Cell Activation Positive Regulation Of Cell Death Histone Exchange Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis DNA Replication-independent Nucleosome Assembly Leukocyte Degranulation Cytoplasmic Transport Regulation Of Vesicle Fusion Regulation Of Synaptic Vesicle Transport Cellular Localization Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Regulated Secretory Pathway Chordate Embryonic Development Centromere Complex Assembly Embryo Development Ending In Birth Or Egg Hatching
Tagcloud ?			akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping hook3 integrative massively men1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl
Tagcloud (Difference) ?			akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping hook3 integrative massively men1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl
Tagcloud (Intersection) ?