CENPU and PGRMC1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CENPU	PGRMC1
Gene Name		centromere protein U	progesterone receptor membrane component 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Microtubule Organizing Center Cytosol	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function		Steroid Binding Protein Binding Heme Binding
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Viral Process CENP-A Containing Nucleosome Assembly Chordate Embryonic Development	Axon Guidance
Pathways		Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: EIF4G1 GIT1 LAMC1 MLF1 NDUFS2 NUP62 PGRMC1 PLK1 PLK2 PLK3 PLXNB2 ROBO2 SPTBN4 TFIP11 TUBB2B UPF2 XRCC6	5 interactors: CENPU CREB3L1 MTNR1A PAM16 SCAP
Entrez ID		79682	10857
HPRD ID		14722	02338
Ensembl ID		ENSG00000151725	ENSG00000101856
Uniprot IDs		Q09GN2 Q71F23	O00264 Q6IB11
PDB IDs
Enriched GO Terms of Interacting Partners?		Generation Of Neurons Neurogenesis System Development Developmental Process Axon Guidance Nervous System Development Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Cell Differentiation Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Locomotion Positive Regulation Of Cellular Protein Catabolic Process Neuron Projection Development Mitotic Cell Cycle Checkpoint Endomembrane System Organization Regulation Of Cellular Protein Metabolic Process Cell Projection Morphogenesis Negative Regulation Of Cell Cycle Cell Part Morphogenesis Mitotic Nuclear Envelope Disassembly Regulation Of Cell Cycle Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Movement Of Cell Or Subcellular Component Nuclear Envelope Disassembly Neuron Development Regulation Of Protein Metabolic Process Response To Stimulus Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Cell Cycle Process Cell Morphogenesis Regulation Of Cell Division Spliceosomal Complex Disassembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cytokinesis Neuron Differentiation Cell Projection Organization Nuclear Envelope Organization	ER-nucleus Signaling Pathway Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Protein Import Into Mitochondrial Matrix Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process SREBP Signaling Pathway Negative Regulation Of ATPase Activity Positive Regulation Of Receptor Biosynthetic Process Response To Sterol Depletion Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Regulation Of Receptor Biosynthetic Process Positive Regulation Of CGMP Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of CGMP Metabolic Process Regulation Of CGMP Biosynthetic Process Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Steroid Metabolic Process CENP-A Containing Nucleosome Assembly Regulation Of Cholesterol Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of CGMP Metabolic Process Histone Exchange Mating Behavior DNA Replication-independent Nucleosome Assembly Regulation Of Nitrogen Compound Metabolic Process Regulation Of ATPase Activity Negative Regulation Of Lipid Biosynthetic Process Centromere Complex Assembly Intracellular Protein Transmembrane Transport Positive Regulation Of Cellular Metabolic Process
Tagcloud ?			abeta25 ag205 alleviated attempted attenuate attenuates brings broadly classic complementary entitled exerts inhibiting insults jnk mitochondria nervous neuroprotection neuroprotections neuroprotective neurosteroid pr progesterone protected protective rescuing ru486 special steroids
Tagcloud (Difference) ?			abeta25 ag205 alleviated attempted attenuate attenuates brings broadly classic complementary entitled exerts inhibiting insults jnk mitochondria nervous neuroprotection neuroprotections neuroprotective neurosteroid pr progesterone protected protective rescuing ru486 special steroids
Tagcloud (Intersection) ?