PPP3CA and MYOZ2

Number of citations of the paper that reports this interaction (PMID 11842093)
29

Data Source:
HPRD (in vivo, two hybrid)

		PPP3CA	MYOZ2
Gene Name		protein phosphatase 3, catalytic subunit, alpha isozyme	myozenin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Calcineurin Complex Z Disc Sarcolemma	Actin Cytoskeleton Sarcomere Z Disc
	Molecular Function	Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Drug Binding Enzyme Binding Calmodulin-dependent Protein Phosphatase Activity Protein Heterodimerization Activity Protein Dimerization Activity	Actin Binding Protein Binding Protein Phosphatase 2B Binding Telethonin Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Response To Amphetamine Protein Dephosphorylation Protein Import Into Nucleus Calcium Ion Transport Transition Between Fast And Slow Fiber Dephosphorylation Calcineurin-NFAT Signaling Cascade Multicellular Organismal Response To Stress Cellular Response To Drug Fc-epsilon Receptor Signaling Pathway T Cell Activation Innate Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Insulin Secretion Skeletal Muscle Fiber Development Regulation Of Synaptic Transmission Positive Regulation Of NFAT Protein Import Into Nucleus Response To Calcium Ion Regulation Of Excitatory Postsynaptic Membrane Potential Cellular Response To Glucose Stimulus Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress	Biological_process
Pathways		Signaling by GPCR Ca2+ pathway Opioid Signalling DARPP-32 events Fc epsilon receptor (FCERI) signaling FCERI mediated Ca+2 mobilization Signaling by Wnt Innate Immune System beta-catenin independent WNT signaling
Drugs
Diseases
GWAS		Blood pressure ( 22763476) Corneal structure ( 21979947)
Protein-Protein Interactions		24 interactors: AKAP5 ATP2B4 BAD BCL2 C16orf74 CABIN1 CASP3 CRTC2 FKBP1A FKBP8 GABRA1 GABRB2 GABRG2 GRB2 KCNIP3 MARCH7 MYOZ2 MYOZ3 PPP3R1 PRKCZ RCAN1 RCAN2 SOD1 SYNJ1	12 interactors: ACTN1 ACTN2 ACTN4 DRICH1 EWSR1 FLNC LDB3 MYB PPP3CA PPP3CB RBPMS ZDHHC17
Entrez ID		5530	51778
HPRD ID		00234	05724
Ensembl ID		ENSG00000138814	ENSG00000172399
Uniprot IDs		Q08209	Q9NPC6
PDB IDs		1AUI 1M63 1MF8 2JOG 2JZI 2P6B 2R28 2W73 3LL8 4F0Z
Enriched GO Terms of Interacting Partners?		Response To Organonitrogen Compound Cellular Response To Organonitrogen Compound Signaling Cell Communication Behavior Cellular Response To Histamine Synaptic Transmission, GABAergic Response To Organic Cyclic Compound Calcineurin-NFAT Signaling Cascade Response To Histamine Single-organism Behavior Regulation Of Neuron Death Cellular Response To Stimulus Cellular Response To Organic Substance Regulation Of Phosphorus Metabolic Process Response To Organic Substance Signal Transduction Inositol Phosphate-mediated Signaling Cellular Response To Ammonium Ion Positive Regulation Of Signal Transduction Regulation Of Lymphocyte Activation Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Response To Organic Cyclic Compound Response To Oxidative Stress Regulation Of Neuron Apoptotic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Apoptotic Process Release Of Cytochrome C From Mitochondria Gamma-aminobutyric Acid Signaling Pathway Regulation Of Cell Activation Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cell Death Cell Surface Receptor Signaling Pathway Neurological System Process Positive Regulation Of Cellular Metabolic Process Regulation Of T Cell Activation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Response To Stimulus Synaptic Transmission Negative Regulation Of Apoptotic Process Cell-cell Signaling Regulation Of Immune System Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Phosphorylation Negative Regulation Of Programmed Cell Death Regulation Of Cell Adhesion Transport Regulation Of Cell-cell Adhesion Negative Regulation Of Cell Death	Protein Localization To Tight Junction Cell Activation Cell Junction Assembly Calcineurin-NFAT Signaling Cascade Protein Localization To Cell Junction Platelet Degranulation Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transport Exocytosis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Inositol Phosphate-mediated Signaling Actin Crosslink Formation Blood Coagulation Hemostasis Striated Muscle Cell Development Positive Regulation Of Intracellular Protein Transport Muscle Cell Development Regulation Of Protein Import Into Nucleus Secretion By Cell Platelet Activation Regulation Of Protein Localization To Nucleus Focal Adhesion Assembly Regulation Of Body Fluid Levels Cell-cell Junction Organization Regulation Of Nucleocytoplasmic Transport Wound Healing Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Striated Muscle Cell Differentiation Regulation Of RNA Metabolic Process Secretion Actin Filament-based Process Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Intracellular Transport Tight Junction Assembly Regulation Of Intracellular Protein Transport Response To Wounding Adherens Junction Assembly Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Cellular Response To Drug Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transporter Activity Regulation Of Protein Localization Muscle Cell Differentiation Actin Filament Bundle Assembly Positive Regulation Of Protein Transport
Tagcloud ?		adenocarcinoma chip coding cre dt ductal fresh g12d intraepithelial kras lincrna1611 lncrnas lsl neoplasia operation pan pancreatic panin pca pdac pdx profilings r172h resected rnas sh tissues tp53 weak	actinin aligned bigenic calcineurin cardiomyopathy constituted disk disks flag gross hcm hemizygous hypertrophic hypertrophy i246m jnk54 lentiviral likewise luc mal myozenin nfatc pp2b ppp3cb quantifying rcan1 s48p transgene unsettled
Tagcloud (Difference) ?		adenocarcinoma chip coding cre dt ductal fresh g12d intraepithelial kras lincrna1611 lncrnas lsl neoplasia operation pan pancreatic panin pca pdac pdx profilings r172h resected rnas sh tissues tp53 weak	actinin aligned bigenic calcineurin cardiomyopathy constituted disk disks flag gross hcm hemizygous hypertrophic hypertrophy i246m jnk54 lentiviral likewise luc mal myozenin nfatc pp2b ppp3cb quantifying rcan1 s48p transgene unsettled
Tagcloud (Intersection) ?