GLUD1 and SEC62

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GLUD1	SEC62
Gene Name		glutamate dehydrogenase 1	SEC62 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Integral Component Of Membrane Aggresome Intermediate Filament Cytoskeleton
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding	Receptor Activity Protein Transporter Activity
	Biological Process	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process Tricarboxylic Acid Metabolic Process	Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Membrane
Pathways		Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives
Drugs		L-Glutamic Acid NADH Hexachlorophene Nicotinamide-Adenine-Dinucleotide Adenosine-5\'-Diphosphate Guanosine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ASGR2 CRP DYNLL1 GOT2 HPX LSM1 NR4A1 ORM1 SEC62 STAT5A VTN	4 interactors: CIC GLUD1 SEC63 ZNF24
Entrez ID		2746	7095
HPRD ID		11748	03706
Ensembl ID		ENSG00000148672	ENSG00000008952
Uniprot IDs		B3KV55 E9KL48 P00367	Q99442
PDB IDs		1L1F 1NR1
Enriched GO Terms of Interacting Partners?		Regulation Of Immune System Process 2-oxoglutarate Metabolic Process Regulation Of Immune Response Oxaloacetate Metabolic Process Transport Acute-phase Response Endocytosis Regulation Of Humoral Immune Response Positive Regulation Of Mast Cell Differentiation Receptor-mediated Endocytosis Acute Inflammatory Response Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Regulation Of Mast Cell Differentiation Fumarate Metabolic Process Development Of Secondary Male Sexual Characteristics Immune System Process Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Hormone-mediated Signaling Pathway Response To Ethanol Negative Regulation Of Mast Cell Apoptotic Process L-kynurenine Metabolic Process Creatinine Metabolic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response Regulation Of Mast Cell Apoptotic Process Positive Regulation Of Mast Cell Proliferation Positive Regulation Of Immune Response Glutamate Catabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Vesicle-mediated Transport Positive Regulation Of Innate Immune Response Taurine Metabolic Process Aspartate Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Posttranslational Protein Targeting To Membrane Negative Regulation Of Vasodilation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Erythrocyte Differentiation Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Prolactin Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation	Posttranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Membrane System Development Glutamate Catabolic Process Glutamate Biosynthetic Process Multicellular Organismal Development Anatomical Structure Development Dicarboxylic Acid Catabolic Process Developmental Process Nitrogen Compound Metabolic Process Glutamate Metabolic Process
Tagcloud ?		alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily	a181 apparatus bip cytosolically defect inability kar2 kar2p kurihara lies lumenal membranebound mimics nelson passage polypeptide relieve rose sanders schekman sec63 sec63p stalling suppressors transit transiting unimpaired vogel whitfield
Tagcloud (Difference) ?		alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily	a181 apparatus bip cytosolically defect inability kar2 kar2p kurihara lies lumenal membranebound mimics nelson passage polypeptide relieve rose sanders schekman sec63 sec63p stalling suppressors transit transiting unimpaired vogel whitfield
Tagcloud (Intersection) ?