SH2D1A and LHX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SH2D1A	LHX4
Gene Name		SH2 domain containing 1A	LIM homeobox 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding	Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Humoral Immune Response Cellular Defense Response Cell-cell Signaling Positive Regulation Of Signal Transduction Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity	Placenta Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Motor Neuron Axon Guidance Organ Morphogenesis Medial Motor Column Neuron Differentiation Negative Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ARHGEF6 ARHGEF7 CD84 DOK1 EGFR ERBB3 FYB FYN GRB2 LCK LHX4 LY9 MAPK1 MAPK11 MAPK14 SLAMF1 SLAMF6 SLAMF7 TNK2	12 interactors: CHCHD2 FDX1L IFT172 ISL1 LDB2 LONRF1 ORC6 SH2D1A SNRNP25 SSX1 TXNDC5 USP2
Entrez ID		4068	89884
HPRD ID		02390	03686
Ensembl ID		ENSG00000183918
Uniprot IDs		O60880	Q969G2
PDB IDs		1D1Z 1D4T 1D4W 1KA6 1KA7 1M27
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Immune System Process Immune Response-regulating Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Intracellular Signal Transduction Innate Immune Response Immune Response Defense Response Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Immune Response Locomotion Response To Fibroblast Growth Factor Immune Response-regulating Cell Surface Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Fc-epsilon Receptor Signaling Pathway Cellular Response To Organic Substance Cell Activation Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Fc Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Regulation Of Intracellular Signal Transduction Regulation Of Immune System Process Protein Phosphorylation Wound Healing Chemotaxis Response To Stimulus Phosphorylation Positive Regulation Of Immune Response Platelet Activation Response To Organic Substance Axon Guidance Response To Wounding Blood Coagulation Ras Protein Signal Transduction Hemostasis Positive Regulation Of Protein Phosphorylation MAPK Cascade Response To Stress Signal Transduction Cellular Response To Organonitrogen Compound Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Peptide	Spinal Cord Motor Neuron Differentiation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord
Tagcloud ?		abl1 abl2 arrays bcar3 btk crk domains elisas exquisite fabricated fyn grap2 identity lck lyn monospecific nck1 phage pik3r1 plcgamma1 ptpn11 rasa1 resultant selections shc1 syk vav1 zap70	add besides clinician concern congenital correct costly deviation disturb emphasis genetics ghr ghrhr height hesx1 hypothalamus igfr know lhx3 manifestation normality nutrition ones origins pituitary pou1f1 prop1 psychosocial stature
Tagcloud (Difference) ?		abl1 abl2 arrays bcar3 btk crk domains elisas exquisite fabricated fyn grap2 identity lck lyn monospecific nck1 phage pik3r1 plcgamma1 ptpn11 rasa1 resultant selections shc1 syk vav1 zap70	add besides clinician concern congenital correct costly deviation disturb emphasis genetics ghr ghrhr height hesx1 hypothalamus igfr know lhx3 manifestation normality nutrition ones origins pituitary pou1f1 prop1 psychosocial stature
Tagcloud (Intersection) ?