LHX4 and SNRNP25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LHX4	SNRNP25
Gene Name		LIM homeobox 4	small nuclear ribonucleoprotein 25kDa (U11/U12)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Intercellular Bridge
	Molecular Function	Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Placenta Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Motor Neuron Axon Guidance Organ Morphogenesis Medial Motor Column Neuron Differentiation Negative Regulation Of Apoptotic Process	MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CHCHD2 FDX1L IFT172 ISL1 LDB2 LONRF1 ORC6 SH2D1A SNRNP25 SSX1 TXNDC5 USP2	9 interactors: C11orf57 CPSF7 EFHC2 KRT31 LHX4 LNX1 REL TRAF2 UBC
Entrez ID		89884	79622
HPRD ID		03686	12673
Ensembl ID
Uniprot IDs		Q969G2	Q9BV90
PDB IDs
Enriched GO Terms of Interacting Partners?		Spinal Cord Motor Neuron Differentiation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord	I-kappaB Kinase/NF-kappaB Signaling NIK/NF-kappaB Signaling Negative Regulation Of Cell Death Positive Regulation Of Cytokine Production TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Protein Oligomerization Toll-like Receptor 4 Signaling Pathway Regulation Of Cytokine Production Toll-like Receptor Signaling Pathway Protein Ubiquitination Regulation Of Cell Death Protein Modification By Small Protein Conjugation Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Catabolic Process Medial Motor Column Neuron Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Response To Cytokine Protein Polyubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Positive Regulation Of Innate Immune Response Transcription From RNA Polymerase II Promoter Negative Regulation Of Neuron Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Glial Cell Apoptotic Process Protein Processing Somatic Motor Neuron Differentiation Regulation Of Innate Immune Response Protein Homooligomerization Transcription, DNA-templated Protein Complex Assembly Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity RNA Biosynthetic Process Positive Regulation Of Protein Homodimerization Activity Regulation Of Neuron Death Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Viral Protein Processing Cellular Response To Nitric Oxide Positive Regulation Of Interleukin-12 Biosynthetic Process
Tagcloud ?		add besides clinician concern congenital correct costly deviation disturb emphasis genetics ghr ghrhr height hesx1 hypothalamus igfr know lhx3 manifestation normality nutrition ones origins pituitary pou1f1 prop1 psychosocial stature	12q alk backgroundthe ccnd3 conclusionsour ews fli1 foxo1 fusion fusions harbor inactivating kcnmb4 lrp1 methodstranscriptome opportunities osteosarcoma osteosarcomas pax3 resultsnine sanger saos sarcomas ssx1 ssx2 syt tpm3 tpm4 transcriptome
Tagcloud (Difference) ?		add besides clinician concern congenital correct costly deviation disturb emphasis genetics ghr ghrhr height hesx1 hypothalamus igfr know lhx3 manifestation normality nutrition ones origins pituitary pou1f1 prop1 psychosocial stature	12q alk backgroundthe ccnd3 conclusionsour ews fli1 foxo1 fusion fusions harbor inactivating kcnmb4 lrp1 methodstranscriptome opportunities osteosarcoma osteosarcomas pax3 resultsnine sanger saos sarcomas ssx1 ssx2 syt tpm3 tpm4 transcriptome
Tagcloud (Intersection) ?