LRPAP1 and RANBP2

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		LRPAP1	RANBP2
Gene Name		low density lipoprotein receptor-related protein associated protein 1	RAN binding protein 2
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Plasma Membrane Cell Surface Integral Component Of Membrane Vesicle Rough Endoplasmic Reticulum Lumen	Nuclear Pore Mitochondrion Cytosol Membrane Nuclear Membrane Nuclear Inclusion Body Nuclear Pore Nuclear Basket
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Heparin Binding Lipase Binding Receptor Antagonist Activity Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding Very-low-density Lipoprotein Particle Receptor Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Zinc Ion Binding Ran GTPase Binding Ligase Activity
	Biological Process	Protein Folding Receptor-mediated Endocytosis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Vesicle-mediated Transport Negative Regulation Of Protein Binding Extracellular Negative Regulation Of Signal Transduction Negative Regulation Of Beta-amyloid Clearance	Mitotic Cell Cycle Protein Peptidyl-prolyl Isomerization Carbohydrate Metabolic Process Protein Folding Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Protein Sumoylation Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Glucokinase Activity Small Molecule Metabolic Process MRNA Transport Transmembrane Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ETV7 LDLR LRP1 LRP1B LRP2 LRP8 MAPK1 MAPK3 POLA2 PPM1G RAF1 RALA RALGDS RANBP2 RTN4 SORL1 SORT1 VLDLR	34 interactors: AKAP13 ARID4B CALM1 CDCA8 CUL1 FHOD1 HDAC4 IFT140 IPO5 KPNA1 KPNA2 KPNB1 LRPAP1 MDM2 NUP62 NXF1 OPN1LW OPN1MW PARK2 RAN RANGAP1 SAE1 SENP1 SP100 SUMO1 TAF1 TNPO1 TOP2B TP53 UBA2 UBE2I UBTD1 XPO1 XPOT
Entrez ID		4043	5903
HPRD ID		00082	03111
Ensembl ID			ENSG00000153201
Uniprot IDs		P30533	P49792
PDB IDs		1LRE 1NRE 1OP1 1OV2 2FCW 2FTU 2FYL 2P01 2P03	1RRP 1XKE 1Z5S 3UIN 3UIO 3UIP 4GA0 4I9Y 4L6E 4LQW
Enriched GO Terms of Interacting Partners?		Receptor-mediated Endocytosis Endocytosis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Vesicle-mediated Transport Cellular Response To Growth Factor Stimulus Response To Growth Factor Phototransduction, Visible Light Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Retinoid Metabolic Process Transport Ras Protein Signal Transduction Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Signal Transduction Regulation Of Kinase Activity Steroid Metabolic Process Detection Of Light Stimulus Cholesterol Metabolic Process Signaling Isoprenoid Metabolic Process Regulation Of Catalytic Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Transferase Activity Sterol Metabolic Process Cell Communication Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Regulation Of Golgi Inheritance Regulation Of Cellular Component Organization Alcohol Metabolic Process Caveolin-mediated Endocytosis Regulation Of Phosphorus Metabolic Process Detection Of Abiotic Stimulus Response To Abiotic Stimulus Reelin-mediated Signaling Pathway Regulation Of Protein Kinase Activity Regulation Of Golgi Organization Cellular Response To Stimulus Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Locomotion Response To External Stimulus Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Regulation Of Phosphorylation Response To Organic Substance Regulation Of Early Endosome To Late Endosome Transport Viral Process	Viral Process Nucleocytoplasmic Transport Nuclear Transport Protein Localization To Nucleus Protein Localization To Organelle Cytoplasmic Transport Peptidyl-lysine Modification Protein Import Into Nucleus Nuclear Import Cellular Localization Protein Sumoylation Protein Import NLS-bearing Protein Import Into Nucleus Positive Regulation Of Metabolic Process Cellular Protein Localization Establishment Of Localization In Cell Intracellular Transport Mitotic Cell Cycle Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Protein Localization Regulation Of Intracellular Transport Regulation Of Nucleocytoplasmic Transport Establishment Of Protein Localization To Organelle Nuclear Export Cellular Response To Organic Substance Regulation Of Protein Localization Regulation Of Protein Catabolic Process Cell Cycle Regulation Of Intracellular Protein Transport Protein Targeting Protein Modification By Small Protein Conjugation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Binding Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Establishment Of Protein Localization SMT3-dependent Protein Catabolic Process Intracellular Protein Transport Positive Regulation Of Cellular Protein Catabolic Process Response To Organic Substance Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Establishment Of Protein Localization Regulation Of Cell Cycle Positive Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Gene Expression Peptidyl-amino Acid Modification Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?			adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 respective rps6kl1 sequenced sncaip spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Difference) ?			adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 respective rps6kl1 sequenced sncaip spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Intersection) ?