LRPAP1 and LRP1B

Number of citations of the paper that reports this interaction (PMID 11384978)
14

Data Source:
HPRD (in vivo)

		LRPAP1	LRP1B
Gene Name		low density lipoprotein receptor-related protein associated protein 1	low density lipoprotein receptor-related protein 1B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Plasma Membrane Cell Surface Integral Component Of Membrane Vesicle Rough Endoplasmic Reticulum Lumen	Integral Component Of Membrane Receptor Complex
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Heparin Binding Lipase Binding Receptor Antagonist Activity Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding Very-low-density Lipoprotein Particle Receptor Binding	Low-density Lipoprotein Receptor Activity Calcium Ion Binding
	Biological Process	Protein Folding Receptor-mediated Endocytosis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Vesicle-mediated Transport Negative Regulation Of Protein Binding Extracellular Negative Regulation Of Signal Transduction Negative Regulation Of Beta-amyloid Clearance	Receptor-mediated Endocytosis Protein Transport
Pathways
Drugs
Diseases
GWAS			Aging ( 19367585) Body mass index ( 20935630) Erectile dysfunction and prostate cancer treatment ( 20932654) Menarche (age at onset) ( 21102462) Optic disc size (disc) ( 20395239)
Protein-Protein Interactions		18 interactors: ETV7 LDLR LRP1 LRP1B LRP2 LRP8 MAPK1 MAPK3 POLA2 PPM1G RAF1 RALA RALGDS RANBP2 RTN4 SORL1 SORT1 VLDLR	5 interactors: APP LRPAP1 PLAT PLAUR SERPINE1
Entrez ID		4043	53353
HPRD ID		00082	16383
Ensembl ID			ENSG00000168702
Uniprot IDs		P30533	Q9NZR2
PDB IDs		1LRE 1NRE 1OP1 1OV2 2FCW 2FTU 2FYL 2P01 2P03
Enriched GO Terms of Interacting Partners?		Receptor-mediated Endocytosis Endocytosis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Vesicle-mediated Transport Cellular Response To Growth Factor Stimulus Response To Growth Factor Phototransduction, Visible Light Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Retinoid Metabolic Process Transport Ras Protein Signal Transduction Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Signal Transduction Regulation Of Kinase Activity Steroid Metabolic Process Detection Of Light Stimulus Cholesterol Metabolic Process Signaling Isoprenoid Metabolic Process Regulation Of Catalytic Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Transferase Activity Sterol Metabolic Process Cell Communication Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Regulation Of Golgi Inheritance Regulation Of Cellular Component Organization Alcohol Metabolic Process Caveolin-mediated Endocytosis Regulation Of Phosphorus Metabolic Process Detection Of Abiotic Stimulus Response To Abiotic Stimulus Reelin-mediated Signaling Pathway Regulation Of Protein Kinase Activity Regulation Of Golgi Organization Cellular Response To Stimulus Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Locomotion Response To External Stimulus Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Regulation Of Phosphorylation Response To Organic Substance Regulation Of Early Endosome To Late Endosome Transport Viral Process	Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Blood Coagulation Hemostasis Regulation Of Blood Coagulation Regulation Of Receptor Activity Regulation Of Wound Healing Regulation Of Body Fluid Levels Wound Healing Regulation Of Proteolysis Response To Wounding Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Processing Platelet Degranulation Negative Regulation Of Vascular Wound Healing Urokinase Plasminogen Activator Signaling Pathway Positive Regulation Of Leukotriene Production Involved In Inflammatory Response Regulation Of Protein Metabolic Process Regulation Of Protein Binding Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Protein Metabolic Process Positive Regulation Of Ovulation Regulation Of Smooth Muscle Cell-matrix Adhesion Collateral Sprouting In Absence Of Injury Chronological Cell Aging Negative Regulation Of Beta-amyloid Clearance Platelet Activation Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Regulation Of Vascular Wound Healing Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Regulation Of Signaling Axon Choice Point Recognition Regulation Of Beta-amyloid Clearance Negative Regulation Of Cell Adhesion Mediated By Integrin Locomotion Cell Surface Receptor Signaling Pathway Plasminogen Activation Negative Regulation Of Plasminogen Activation Neuron Remodeling Exocytosis
Tagcloud ?			adiposity brown bxh2 classes cub determinants encompassing fractions haplotype inbred lipoprotein lx microsatellite norway permutations polymorphic pxo segregate shr silico spanning subdivision sucrose suggestive tg trait traits triglyceride vldl
Tagcloud (Difference) ?			adiposity brown bxh2 classes cub determinants encompassing fractions haplotype inbred lipoprotein lx microsatellite norway permutations polymorphic pxo segregate shr silico spanning subdivision sucrose suggestive tg trait traits triglyceride vldl
Tagcloud (Intersection) ?