LGALS3BP and LGALS3

Number of citations of the paper that reports this interaction (PMID 8813152)
21

Data Source:
HPRD (in vitro, in vivo)

		LGALS3BP	LGALS3
Gene Name		lectin, galactoside-binding, soluble, 3 binding protein	lectin, galactoside-binding, soluble, 3
Image
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Membrane Extracellular Matrix Extracellular Vesicular Exosome Blood Microparticle	Immunological Synapse Proteinaceous Extracellular Matrix Extracellular Space Nucleus Spliceosomal Complex Cytoplasm Mitochondrial Inner Membrane Plasma Membrane External Side Of Plasma Membrane Membrane Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Scavenger Receptor Activity	Protein Binding IgE Binding Carbohydrate Binding Chemoattractant Activity Laminin Binding Poly(A) RNA Binding
	Biological Process	Receptor-mediated Endocytosis Cellular Defense Response Cell Adhesion Signal Transduction	Skeletal System Development Monocyte Chemotaxis MRNA Processing RNA Splicing Extracellular Matrix Organization Neutrophil Chemotaxis Epithelial Cell Differentiation Regulation Of T Cell Proliferation Innate Immune Response Negative Regulation Of Endocytosis Eosinophil Chemotaxis Macrophage Chemotaxis Negative Regulation Of T Cell Receptor Signaling Pathway Positive Chemotaxis Regulation Of T Cell Apoptotic Process Mononuclear Cell Migration Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Import Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Immunological Synapse Formation Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Advanced glycosylation endproduct receptor signaling Innate Immune System
Drugs
Diseases
GWAS			Protein biomarker ( 23056639)
Protein-Protein Interactions		11 interactors: CD14 COL5A1 COL6A1 FN1 ITGB1 LGALS1 LGALS3 NID1 PPIC SELE XRN1	20 interactors: APP BARD1 C1GALT1C1 CSNK1A1 CSNK2A1 CSNK2A2 CUBN CYHR1 ELN FCGR2A GEMIN4 GOLGA2 LGALS3BP LIM2 MMP2 MYOC PPIG PRR13 SS18L1 SUFU
Entrez ID		3959	3958
HPRD ID		02796	01090
Ensembl ID		ENSG00000108679	ENSG00000131981
Uniprot IDs		B4DWA8 Q08380	P17931
PDB IDs		1BY2	1A3K 1KJL 1KJR 2NMN 2NMO 2NN8 2XG3 3AYA 3AYC 3AYD 3AYE 3T1L 3T1M 3ZSJ 3ZSK 3ZSL 3ZSM 4JC1 4JCK
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Regulation Of Endocytosis Calcium-independent Cell-matrix Adhesion Leukocyte Migration Cell Adhesion Regulation Of Cellular Component Organization Locomotion Response To Wounding Positive Regulation Of Endocytosis Leukocyte Tethering Or Rolling Regulation Of Vesicle-mediated Transport Cell Migration Movement Of Cell Or Subcellular Component Formation Of Primary Germ Layer Cell Motility Cell-matrix Adhesion Response To External Stimulus Regulation Of Cell-substrate Adhesion Cellular Extravasation Gastrulation Cell-substrate Adhesion Wound Healing Chemotaxis Regulation Of Cell Adhesion Endodermal Cell Differentiation Regulation Of Immune System Process Immune System Process Defense Response Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport Response To Stress Endoderm Formation Positive Regulation Of Cell Migration Generation Of Neurons Collagen Catabolic Process Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Negative Regulation Of Immunological Synapse Formation Integrin Biosynthetic Process Positive Regulation Of Erythrocyte Aggregation Neurogenesis Positive Regulation Of Immune System Process Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development Collagen Metabolic Process Tissue Development Axon Guidance	Neuron Differentiation Neuron Projection Development Negative Regulation Of Cellular Protein Catabolic Process Wnt Signaling Pathway Neuron Development Negative Regulation Of Protein Catabolic Process Endocytosis Generation Of Neurons Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Neurogenesis Cell Projection Organization Cell Morphogenesis Involved In Differentiation Regulation Of Protein Catabolic Process Axon Guidance Regulation Of Protein Processing Neuron Maturation Cell Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Axonogenesis Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Morphogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nervous System Development Negative Regulation Of Proteasomal Protein Catabolic Process Neuron Projection Morphogenesis Cell Surface Receptor Signaling Pathway Regulation Of Proteolysis Synaptic Growth At Neuromuscular Junction ERBB2 Signaling Pathway Negative Regulation Of MRNA 3'-end Processing Anatomical Structure Morphogenesis Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Chromosome Organization Collateral Sprouting In Absence Of Injury Mitotic Cell Cycle Extracellular Matrix Disassembly
Tagcloud ?		angptl2 cldn10 cldn4 cst6 dioestrus enpp1 epas1 itgb4 maged1 mep1b metoestrus muc16 oestrogens oestrous oestrus pcsk5 plat preoestrus sepp1 simmental slc11a2 slc16a1 slc1a1 tdgf1 tek timp1 timp2 tjp1	clnd23 clnd8 colorectal cytoscape database david degs detailed differentially downloaded downregulated enriched foxo3 go gse8671 microarray network omnibus ontology pgfdr ppi shed spia string tcf7l2 tfats top upregulated valuable
Tagcloud (Difference) ?		angptl2 cldn10 cldn4 cst6 dioestrus enpp1 epas1 itgb4 maged1 mep1b metoestrus muc16 oestrogens oestrous oestrus pcsk5 plat preoestrus sepp1 simmental slc11a2 slc16a1 slc1a1 tdgf1 tek timp1 timp2 tjp1	clnd23 clnd8 colorectal cytoscape database david degs detailed differentially downloaded downregulated enriched foxo3 go gse8671 microarray network omnibus ontology pgfdr ppi shed spia string tcf7l2 tfats top upregulated valuable
Tagcloud (Intersection) ?