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LGALS3 and CYHR1
Number of citations of the paper that reports this interaction (PMID
10745073
)
5
Data Source:
HPRD
(two hybrid, in vitro)
LGALS3
CYHR1
Gene Name
lectin, galactoside-binding, soluble, 3
cysteine/histidine-rich 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Immunological Synapse
Proteinaceous Extracellular Matrix
Extracellular Space
Nucleus
Spliceosomal Complex
Cytoplasm
Mitochondrial Inner Membrane
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Extracellular Matrix
Extracellular Vesicular Exosome
Nuclear Envelope
Nucleoplasm
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
IgE Binding
Carbohydrate Binding
Chemoattractant Activity
Laminin Binding
Poly(A) RNA Binding
Zinc Ion Binding
Biological Process
Skeletal System Development
Monocyte Chemotaxis
MRNA Processing
RNA Splicing
Extracellular Matrix Organization
Neutrophil Chemotaxis
Epithelial Cell Differentiation
Regulation Of T Cell Proliferation
Innate Immune Response
Negative Regulation Of Endocytosis
Eosinophil Chemotaxis
Macrophage Chemotaxis
Negative Regulation Of T Cell Receptor Signaling Pathway
Positive Chemotaxis
Regulation Of T Cell Apoptotic Process
Mononuclear Cell Migration
Positive Regulation Of Mononuclear Cell Migration
Positive Regulation Of Calcium Ion Import
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Immunological Synapse Formation
Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Advanced glycosylation endproduct receptor signaling
Innate Immune System
Drugs
Diseases
GWAS
Protein biomarker (
23056639
)
Protein-Protein Interactions
20 interactors:
APP
BARD1
C1GALT1C1
CSNK1A1
CSNK2A1
CSNK2A2
CUBN
CYHR1
ELN
FCGR2A
GEMIN4
GOLGA2
LGALS3BP
LIM2
MMP2
MYOC
PPIG
PRR13
SS18L1
SUFU
4 interactors:
ALDH3A1
KPNA4
LGALS3
MAPK9
Entrez ID
3958
50626
HPRD ID
01090
13107
Ensembl ID
ENSG00000131981
ENSG00000187954
Uniprot IDs
P17931
Q6ZMK1
PDB IDs
1A3K
1KJL
1KJR
2NMN
2NMO
2NN8
2XG3
3AYA
3AYC
3AYD
3AYE
3T1L
3T1M
3ZSJ
3ZSK
3ZSL
3ZSM
4JC1
4JCK
Enriched GO Terms of Interacting Partners
?
Neuron Differentiation
Neuron Projection Development
Negative Regulation Of Cellular Protein Catabolic Process
Wnt Signaling Pathway
Neuron Development
Negative Regulation Of Protein Catabolic Process
Endocytosis
Generation Of Neurons
Negative Regulation Of Proteolysis
Negative Regulation Of Protein Processing
Neurogenesis
Cell Projection Organization
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Catabolic Process
Axon Guidance
Regulation Of Protein Processing
Neuron Maturation
Cell Development
Mitotic Spindle Checkpoint
Negative Regulation Of Chromosome Segregation
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Spindle Checkpoint
Axonogenesis
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Metaphase/anaphase Transition
Skeletal Muscle Hypertrophy
ERBB2-ERBB3 Signaling Pathway
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Cell Morphogenesis
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Nervous System Development
Negative Regulation Of Proteasomal Protein Catabolic Process
Neuron Projection Morphogenesis
Cell Surface Receptor Signaling Pathway
Regulation Of Proteolysis
Synaptic Growth At Neuromuscular Junction
ERBB2 Signaling Pathway
Negative Regulation Of MRNA 3'-end Processing
Anatomical Structure Morphogenesis
Negative Regulation Of Cell Division
Regulation Of Chromosome Segregation
Negative Regulation Of Intracellular Protein Transport
Negative Regulation Of Chromosome Organization
Collateral Sprouting In Absence Of Injury
Mitotic Cell Cycle
Extracellular Matrix Disassembly
Negative Regulation Of Immunological Synapse Formation
Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Positive Regulation Of Ion Transport
Response To Stress
Positive Regulation Of Mononuclear Cell Migration
Mononuclear Cell Migration
JUN Phosphorylation
Positive Regulation Of Prostaglandin Biosynthetic Process
Establishment Of Protein Localization To Organelle
Eosinophil Chemotaxis
Eosinophil Migration
Response To External Stimulus
Protein Targeting
Positive Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Prostaglandin Secretion
Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Response To Inorganic Substance
Positive Regulation Of Calcium Ion Import
Monocyte Chemotaxis
Response To Drug
Protein Localization To Organelle
Macrophage Chemotaxis
Positive Regulation Of Icosanoid Secretion
NLS-bearing Protein Import Into Nucleus
Negative Regulation Of T Cell Receptor Signaling Pathway
Cellular Response To Cytokine Stimulus
Regulation Of Calcium Ion Import
Regulation Of Ion Transport
Positive Regulation Of Fatty Acid Transport
Response To Organic Substance
Positive Chemotaxis
Cytoplasmic Transport
Response To Cytokine
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Release Of Cytochrome C From Mitochondria
Positive Regulation Of Fatty Acid Metabolic Process
Regulation Of Fatty Acid Transport
Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Transport
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Response To Organonitrogen Compound
Positive Regulation Of Chemokine Production
Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Response To Lipid
Regulation Of T Cell Apoptotic Process
Regulation Of Macrophage Derived Foam Cell Differentiation
Regulation Of Immune Response
Regulation Of T Cell Receptor Signaling Pathway
Negative Regulation Of Endocytosis
Tagcloud
?
clnd23
clnd8
colorectal
cytoscape
database
david
degs
detailed
differentially
downloaded
downregulated
enriched
foxo3
go
gse8671
microarray
network
omnibus
ontology
pgfdr
ppi
shed
spia
string
tcf7l2
tfats
top
upregulated
valuable
Tagcloud (Difference)
?
clnd23
clnd8
colorectal
cytoscape
database
david
degs
detailed
differentially
downloaded
downregulated
enriched
foxo3
go
gse8671
microarray
network
omnibus
ontology
pgfdr
ppi
shed
spia
string
tcf7l2
tfats
top
upregulated
valuable
Tagcloud (Intersection)
?