LGALS3 and C1GALT1C1

Number of citations of the paper that reports this interaction (PMID 18695044)
24

Data Source:
BioGRID (pull down)

		LGALS3	C1GALT1C1
Gene Name		lectin, galactoside-binding, soluble, 3	C1GALT1-specific chaperone 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Proteinaceous Extracellular Matrix Extracellular Space Nucleus Spliceosomal Complex Cytoplasm Mitochondrial Inner Membrane Plasma Membrane External Side Of Plasma Membrane Membrane Extracellular Matrix Extracellular Vesicular Exosome	Golgi Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding IgE Binding Carbohydrate Binding Chemoattractant Activity Laminin Binding Poly(A) RNA Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Protein Binding
	Biological Process	Skeletal System Development Monocyte Chemotaxis MRNA Processing RNA Splicing Extracellular Matrix Organization Neutrophil Chemotaxis Epithelial Cell Differentiation Regulation Of T Cell Proliferation Innate Immune Response Negative Regulation Of Endocytosis Eosinophil Chemotaxis Macrophage Chemotaxis Negative Regulation Of T Cell Receptor Signaling Pathway Positive Chemotaxis Regulation Of T Cell Apoptotic Process Mononuclear Cell Migration Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Import Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Immunological Synapse Formation Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Protein O-linked Glycosylation O-glycan Processing Platelet Activation Platelet Morphogenesis Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity
Pathways		Advanced glycosylation endproduct receptor signaling Innate Immune System	Post-translational protein modification O-linked glycosylation of mucins O-linked glycosylation
Drugs
Diseases
GWAS		Protein biomarker ( 23056639)
Protein-Protein Interactions		20 interactors: APP BARD1 C1GALT1C1 CSNK1A1 CSNK2A1 CSNK2A2 CUBN CYHR1 ELN FCGR2A GEMIN4 GOLGA2 LGALS3BP LIM2 MMP2 MYOC PPIG PRR13 SS18L1 SUFU	3 interactors: B3GNT2 C1GALT1 LGALS3
Entrez ID		3958	29071
HPRD ID		01090	06462
Ensembl ID		ENSG00000131981	ENSG00000171155
Uniprot IDs		P17931	Q96EU7
PDB IDs		1A3K 1KJL 1KJR 2NMN 2NMO 2NN8 2XG3 3AYA 3AYC 3AYD 3AYE 3T1L 3T1M 3ZSJ 3ZSK 3ZSL 3ZSM 4JC1 4JCK
Enriched GO Terms of Interacting Partners?		Neuron Differentiation Neuron Projection Development Negative Regulation Of Cellular Protein Catabolic Process Wnt Signaling Pathway Neuron Development Negative Regulation Of Protein Catabolic Process Endocytosis Generation Of Neurons Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Neurogenesis Cell Projection Organization Cell Morphogenesis Involved In Differentiation Regulation Of Protein Catabolic Process Axon Guidance Regulation Of Protein Processing Neuron Maturation Cell Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Axonogenesis Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Morphogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nervous System Development Negative Regulation Of Proteasomal Protein Catabolic Process Neuron Projection Morphogenesis Cell Surface Receptor Signaling Pathway Regulation Of Proteolysis Synaptic Growth At Neuromuscular Junction ERBB2 Signaling Pathway Negative Regulation Of MRNA 3'-end Processing Anatomical Structure Morphogenesis Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Chromosome Organization Collateral Sprouting In Absence Of Injury Mitotic Cell Cycle Extracellular Matrix Disassembly	O-glycan Processing Protein O-linked Glycosylation Negative Regulation Of Immunological Synapse Formation Post-translational Protein Modification Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Positive Regulation Of Mononuclear Cell Migration Mononuclear Cell Migration Macromolecule Glycosylation Protein Glycosylation Poly-N-acetyllactosamine Biosynthetic Process Glycosylation Poly-N-acetyllactosamine Metabolic Process Glycoprotein Biosynthetic Process Eosinophil Chemotaxis Glycoprotein Metabolic Process Eosinophil Migration Epithelial Cell Differentiation Positive Regulation Of Calcium Ion Import Monocyte Chemotaxis Intestinal Epithelial Cell Development Chemotaxis Macrophage Chemotaxis Intestinal Epithelial Cell Differentiation Negative Regulation Of T Cell Receptor Signaling Pathway Regulation Of Calcium Ion Import Keratan Sulfate Biosynthetic Process Cell Differentiation Keratan Sulfate Metabolic Process Positive Chemotaxis Cellular Polysaccharide Biosynthetic Process Polysaccharide Biosynthetic Process System Development Carbohydrate Metabolic Process Columnar/cuboidal Epithelial Cell Development Regulation Of T Cell Apoptotic Process Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Endocytosis Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Epithelium Development Neutrophil Chemotaxis Neutrophil Migration Granulocyte Chemotaxis Regulation Of Lymphocyte Apoptotic Process Locomotion Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Ion Transmembrane Transport Polysaccharide Metabolic Process Positive Regulation Of Leukocyte Migration Movement Of Cell Or Subcellular Component
Tagcloud ?		clnd23 clnd8 colorectal cytoscape database david degs detailed differentially downloaded downregulated enriched foxo3 go gse8671 microarray network omnibus ontology pgfdr ppi shed spia string tcf7l2 tfats top upregulated valuable
Tagcloud (Difference) ?		clnd23 clnd8 colorectal cytoscape database david degs detailed differentially downloaded downregulated enriched foxo3 go gse8671 microarray network omnibus ontology pgfdr ppi shed spia string tcf7l2 tfats top upregulated valuable
Tagcloud (Intersection) ?