RPSA and ABCD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPSA	ABCD1
Gene Name		ribosomal protein SA	ATP-binding cassette, sub-family D (ALD), member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Cytosolic Small Ribosomal Subunit 90S Preribosome Extracellular Vesicular Exosome	Cytoplasm Mitochondrion Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding Poly(A) RNA Binding	Transporter Activity Peroxisomal Fatty-acyl-CoA Transporter Activity Protein Binding ATP Binding ATPase Activity Enzyme Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Export From Nucleus Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Adhesion Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Fatty Acid Beta-oxidation Peroxisome Organization Peroxisomal Long-chain Fatty Acid Import Peroxisomal Membrane Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Long-chain Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Linoleic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Transmembrane Transport
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	alpha-linolenic acid (ALA) metabolism ABC-family proteins mediated transport Metabolism of lipids and lipoproteins alpha-linolenic (omega3) and linoleic (omega6) acid metabolism Linoleic acid (LA) metabolism Beta-oxidation of very long chain fatty acids ABCA transporters in lipid homeostasis Peroxisomal lipid metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ABCD1 ACADVL ACD ANKH C6orf106 CALM2 CBX5 CLEC4G CSF2RA DCTN6 GNMT HBG2 HNRNPD IL7R ITGA6 KARS LAMA2 NKX3-1 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3	5 interactors: ABCD2 ABCD3 PEX19 RPSA SLC27A2
Entrez ID		3921	215
HPRD ID		01038	02300
Ensembl ID		ENSG00000168028	ENSG00000101986
Uniprot IDs		P08865	P33897
PDB IDs		3BCH 3J3A
Enriched GO Terms of Interacting Partners?		Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Protein Localization To Chromosome, Telomeric Region Telomere Capping Negative Regulation Of DNA Replication Positive Regulation Of Telomerase Activity Positive Regulation Of Transferase Activity Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Fatty Acid Biosynthetic Process Blood Coagulation Hemostasis Negative Regulation Of Chromosome Organization Regulation Of Telomerase Activity Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Body Fluid Levels Regulation Of DNA Replication Wound Healing Negative Regulation Of Biosynthetic Process Protein Localization To Chromosome Positive Regulation Of DNA Metabolic Process Cellular Response To Organic Substance Telomere Maintenance Via Telomere Lengthening Regulation Of Fatty Acid Biosynthetic Process Response To Wounding Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Protein ADP-ribosylation Lysyl-tRNA Aminoacylation Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Peroxisomal Long-chain Fatty Acid Import Fructose Transport Regulation Of DNA Biosynthetic Process Fatty Acid Beta-oxidation Regulation Of Chromosome Organization Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Metabolic Process Glycogen Metabolic Process Response To Stress Regulation Of Protein ADP-ribosylation Inorganic Diphosphate Transport Positive Regulation Of Androgen Secretion Interleukin-7-mediated Signaling Pathway	Very Long-chain Fatty Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cellular Lipid Catabolic Process Lipid Modification Carboxylic Acid Catabolic Process Lipid Catabolic Process Fatty Acid Metabolic Process Peroxisome Organization Monocarboxylic Acid Metabolic Process Catabolic Process Negative Regulation Of Lipid Binding Methyl-branched Fatty Acid Metabolic Process RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Transport Protein Targeting To Membrane Cellular Lipid Metabolic Process Carboxylic Acid Metabolic Process Peroxisome Membrane Biogenesis Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Establishment Of Protein Localization To Membrane RRNA Transport Organic Acid Metabolic Process RRNA 3'-end Processing Fatty Acid Alpha-oxidation Long-chain Fatty Acid Import Lipid Metabolic Process Protein Import Into Peroxisome Membrane Chaperone-mediated Protein Transport Peroxisomal Membrane Transport Establishment Of Protein Localization To Organelle Ribosomal Small Subunit Assembly Positive Regulation Of Fatty Acid Beta-oxidation Protein Localization To Membrane Oxidation-reduction Process Peroxisome Fission Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Targeting Maturation Of 5.8S RRNA Transmembrane Transport Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Protein Localization To Organelle Bile Acid Biosynthetic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Targeting To Peroxisome
Tagcloud ?		abolish arg357 bonds confer conformational crystal elusive exhibits exquisite hydrogen hydrophobic insights lys303 mode mtb phe307 phe310 poa pyrazinamide pyrazinoic pza questions reveals ribosomal s1 shortening tb terminus tmrna	abcd4 belonging cassette cho eukaryotes fungi gfp h0 homologs hydropathy hydrophobic lacking localization lost mammals metazoan motif nh2 organelle peroxisomes plot possesses possessing segment subcellular subfamily terminal
Tagcloud (Difference) ?		abolish arg357 bonds confer conformational crystal elusive exhibits exquisite hydrogen insights lys303 mode mtb phe307 phe310 poa pyrazinamide pyrazinoic pza questions reveals ribosomal s1 shortening tb terminus tmrna	abcd4 belonging cassette cho eukaryotes fungi gfp h0 homologs hydropathy lacking localization lost mammals metazoan motif nh2 organelle peroxisomes plot possesses possessing segment subcellular subfamily terminal
Tagcloud (Intersection) ?		hydrophobic