ABCD1 and SLC27A2

Number of citations of the paper that reports this interaction (PMID 16781659)
6

Data Source:
BioGRID (unspecified method)

		ABCD1	SLC27A2
Gene Name		ATP-binding cassette, sub-family D (ALD), member 1	solute carrier family 27 (fatty acid transporter), member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Cytosol Membrane Perinuclear Region Of Cytoplasm	Mitochondrion Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity Peroxisomal Fatty-acyl-CoA Transporter Activity Protein Binding ATP Binding ATPase Activity Enzyme Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances Identical Protein Binding Protein Homodimerization Activity	Long-chain Fatty Acid-CoA Ligase Activity Receptor Binding ATP Binding Fatty Acid Transporter Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity
	Biological Process	Fatty Acid Beta-oxidation Peroxisome Organization Peroxisomal Long-chain Fatty Acid Import Peroxisomal Membrane Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Long-chain Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Linoleic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Transmembrane Transport	Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Bile Acid Metabolic Process Very Long-chain Fatty Acid Catabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Long-chain Fatty Acid Import Methyl-branched Fatty Acid Metabolic Process
Pathways		alpha-linolenic acid (ALA) metabolism ABC-family proteins mediated transport Metabolism of lipids and lipoproteins alpha-linolenic (omega3) and linoleic (omega6) acid metabolism Linoleic acid (LA) metabolism Beta-oxidation of very long chain fatty acids ABCA transporters in lipid homeostasis Peroxisomal lipid metabolism	Alpha-oxidation of phytanate Bile acid and bile salt metabolism Synthesis of bile acids and bile salts via 24-hydroxycholesterol Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts Peroxisomal lipid metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ABCD2 ABCD3 PEX19 RPSA SLC27A2	3 interactors: ABCD1 PEX5 YWHAQ
Entrez ID		215	11001
HPRD ID		02300	11935
Ensembl ID		ENSG00000101986	ENSG00000140284
Uniprot IDs		P33897	O14975
PDB IDs
Enriched GO Terms of Interacting Partners?		Very Long-chain Fatty Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cellular Lipid Catabolic Process Lipid Modification Carboxylic Acid Catabolic Process Lipid Catabolic Process Fatty Acid Metabolic Process Peroxisome Organization Monocarboxylic Acid Metabolic Process Catabolic Process Negative Regulation Of Lipid Binding Methyl-branched Fatty Acid Metabolic Process RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Transport Protein Targeting To Membrane Cellular Lipid Metabolic Process Carboxylic Acid Metabolic Process Peroxisome Membrane Biogenesis Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Establishment Of Protein Localization To Membrane RRNA Transport Organic Acid Metabolic Process RRNA 3'-end Processing Fatty Acid Alpha-oxidation Long-chain Fatty Acid Import Lipid Metabolic Process Protein Import Into Peroxisome Membrane Chaperone-mediated Protein Transport Peroxisomal Membrane Transport Establishment Of Protein Localization To Organelle Ribosomal Small Subunit Assembly Positive Regulation Of Fatty Acid Beta-oxidation Protein Localization To Membrane Oxidation-reduction Process Peroxisome Fission Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Targeting Maturation Of 5.8S RRNA Transmembrane Transport Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Protein Localization To Organelle Bile Acid Biosynthetic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Targeting To Peroxisome	Peroxisomal Membrane Transport Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Peroxisome Organization Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cellular Lipid Catabolic Process Peroxisomal Long-chain Fatty Acid Import Lipid Modification Carboxylic Acid Catabolic Process Negative Regulation Of Protein Homotetramerization Intracellular Transport Lipid Catabolic Process Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Fatty Acid Metabolic Process Establishment Of Localization In Cell Very Long-chain Fatty Acid Catabolic Process Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Protein Targeting Long-chain Fatty Acid Catabolic Process Cellular Localization Negative Regulation Of Protein Oligomerization Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Linoleic Acid Metabolic Process Monocarboxylic Acid Metabolic Process Protein Import Into Peroxisome Matrix Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Brain Development Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Head Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Membrane Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intracellular Protein Transport Substantia Nigra Development Cellular Lipid Metabolic Process Central Nervous System Development Long-chain Fatty Acid Transport Endoplasmic Reticulum Organization Carboxylic Acid Metabolic Process Positive Regulation Of Multicellular Organism Growth Intracellular Protein Transmembrane Transport
Tagcloud ?		abcd4 belonging cassette cho eukaryotes fungi gfp h0 homologs hydropathy hydrophobic lacking localization lost mammals metazoan motif nh2 organelle peroxisomes plot possesses possessing segment subcellular subfamily terminal	absent adds biomarkers breastfed breastfeeding confer cpt1a discriminate distinguish dyslipidaemia dyslipidaemic fasn fed formula homa idefics indicative infant insr lepr lifestyle mentioned metabolic overweight pbc pbcs pparalpha transcript triglyceride
Tagcloud (Difference) ?		abcd4 belonging cassette cho eukaryotes fungi gfp h0 homologs hydropathy hydrophobic lacking localization lost mammals metazoan motif nh2 organelle peroxisomes plot possesses possessing segment subcellular subfamily terminal	absent adds biomarkers breastfed breastfeeding confer cpt1a discriminate distinguish dyslipidaemia dyslipidaemic fasn fed formula homa idefics indicative infant insr lepr lifestyle mentioned metabolic overweight pbc pbcs pparalpha transcript triglyceride
Tagcloud (Intersection) ?