KTN1 and RHOG

Number of citations of the paper that reports this interaction (PMID 11689693)
16

Data Source:
HPRD (in vitro, in vivo)

		KTN1	RHOG
Gene Name		kinectin 1 (kinesin receptor)	ras homolog family member G
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Focal Adhesion Extracellular Vesicular Exosome
	Molecular Function	Kinesin Binding Poly(A) RNA Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Microtubule-based Movement	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Axon Guidance Blood Coagulation Metabolic Process Positive Regulation Of Cell Proliferation Rac Protein Signal Transduction Actin Cytoskeleton Organization Platelet Activation Activation Of Rac GTPase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Ruffle Assembly
Pathways			Signaling by GPCR Axon guidance Semaphorin interactions Rho GTPase cycle GPCR downstream signaling Signaling by Rho GTPases GPVI-mediated activation cascade G alpha (12/13) signalling events Sema4D in semaphorin signaling Platelet activation, signaling and aggregation Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AKT1 BNIP3 CDC42 CLEC7A EEF1D IKBKE KIF5B MEOX2 PLEKHA5 RAC1 RHOA RHOG SGTA SYNE4	19 interactors: ARHGDIA ARHGDIG DOCK1 ECT2 ELMO1 ELMO2 ELMOD2 IQGAP2 KTN1 MAP3K11 MCF2 MCF2L PLD1 SMAD1 SMAD4 TGFBR1 VAV1 VAV2 VAV3
Entrez ID		3895	391
HPRD ID		02661	01537
Ensembl ID		ENSG00000126777	ENSG00000177105
Uniprot IDs		B4DZ88 Q5GGW3 Q86UP2	P84095 Q6ICQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Establishment Of Protein Localization To Plasma Membrane Axon Guidance Response To External Stimulus Positive Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of Protein Localization To Plasma Membrane Platelet Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Organization Axonogenesis Regulation Of Signaling T Cell Costimulation Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Epithelium Development Neuron Projection Morphogenesis Ephrin Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Cell Projection Organization Regulation Of Establishment Of Protein Localization Cell Activation Response To Wounding Intracellular Signal Transduction Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Regulation Of Cell Projection Assembly Regulation Of Cellular Component Organization Regulation Of Signal Transduction Regulation Of Protein Localization Defense Response Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Immune Response Establishment Or Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Immune System Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Organelle Organization	Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Catalytic Activity Response To Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Hydrolase Activity Cell Death Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Phagocytosis Signal Transduction Apoptotic Process Programmed Cell Death Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Signaling Cell Surface Receptor Signaling Pathway Cell Communication Regulation Of Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Ras GTPase Activity Positive Regulation Of Rho GTPase Activity Cellular Response To Stimulus Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Fc Receptor Signaling Pathway Regulation Of Rho GTPase Activity Response To Stimulus Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Ras GTPase Activity Regulation Of Signal Transduction Response To Stress Regulation Of Rho Protein Signal Transduction Apoptotic Signaling Pathway Chemotaxis Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway
Tagcloud ?		altering axon caudate circuits clustered cohorts conduct coordinate explained guidance influences influencing intergenic intracranial motivation neuropsychiatric putamen replicable rs945270 shaped stronger strongest subcortical variance variants vesicle volume volumes volumetric	adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Difference) ?		altering axon caudate circuits clustered cohorts conduct coordinate explained guidance influences influencing intergenic intracranial motivation neuropsychiatric putamen replicable rs945270 shaped stronger strongest subcortical variance variants vesicle volume volumes volumetric	adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Intersection) ?