RHOG and ARHGDIG

Number of citations of the paper that reports this interaction (PMID 8939998)
18

Data Source:
HPRD (two hybrid)

		RHOG	ARHGDIG
Gene Name		ras homolog family member G	Rho GDP dissociation inhibitor (GDI) gamma
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Extracellular Vesicular Exosome	Cytosol Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity
	Biological Process	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Axon Guidance Blood Coagulation Metabolic Process Positive Regulation Of Cell Proliferation Rac Protein Signal Transduction Actin Cytoskeleton Organization Platelet Activation Activation Of Rac GTPase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Ruffle Assembly	Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Regulation Of Protein Localization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Signaling by GPCR Axon guidance Semaphorin interactions Rho GTPase cycle GPCR downstream signaling Signaling by Rho GTPases GPVI-mediated activation cascade G alpha (12/13) signalling events Sema4D in semaphorin signaling Platelet activation, signaling and aggregation Sema4D induced cell migration and growth-cone collapse	Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ARHGDIA ARHGDIG DOCK1 ECT2 ELMO1 ELMO2 ELMOD2 IQGAP2 KTN1 MAP3K11 MCF2 MCF2L PLD1 SMAD1 SMAD4 TGFBR1 VAV1 VAV2 VAV3	8 interactors: CDC42 CEP170P1 KXD1 RAC1 RHOA RHOB RHOG RHOH
Entrez ID		391	398
HPRD ID		01537	04163
Ensembl ID		ENSG00000177105	ENSG00000242173
Uniprot IDs		P84095 Q6ICQ8	F1T0H7 Q99819
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Catalytic Activity Response To Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Hydrolase Activity Cell Death Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Phagocytosis Signal Transduction Apoptotic Process Programmed Cell Death Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Signaling Cell Surface Receptor Signaling Pathway Cell Communication Regulation Of Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Ras GTPase Activity Positive Regulation Of Rho GTPase Activity Cellular Response To Stimulus Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Fc Receptor Signaling Pathway Regulation Of Rho GTPase Activity Response To Stimulus Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Ras GTPase Activity Regulation Of Signal Transduction Response To Stress Regulation Of Rho Protein Signal Transduction Apoptotic Signaling Pathway Chemotaxis Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway	Small GTPase Mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Axon Guidance Blood Coagulation Hemostasis Axonogenesis Platelet Activation Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Neuron Projection Morphogenesis Cell Activation Response To Wounding Rho Protein Signal Transduction Cell Morphogenesis Involved In Differentiation Neuron Projection Development Regulation Of Intracellular Signal Transduction Cell Projection Morphogenesis Cell Part Morphogenesis Intracellular Signal Transduction Neuron Development Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Morphogenesis Regulation Of Cell Projection Assembly Neuron Differentiation Cell Projection Organization Regulation Of Cell Projection Organization Locomotion Positive Regulation Of Cell Morphogenesis Involved In Differentiation Actin Cytoskeleton Organization Regulation Of Signal Transduction Actin Filament-based Process Movement Of Cell Or Subcellular Component Cell-cell Junction Organization Generation Of Neurons Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Ras Protein Signal Transduction Regulation Of Signaling Neurogenesis Regulation Of Substrate Adhesion-dependent Cell Spreading Cell Development Cell Migration Response To External Stimulus Substantia Nigra Development Positive Regulation Of Cell Projection Organization Cell Differentiation
Tagcloud ?		adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Difference) ?		adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Intersection) ?