KTN1 and KIF5B

Number of citations of the paper that reports this interaction (PMID 10913441)
9

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		KTN1	KIF5B
Gene Name		kinectin 1 (kinesin receptor)	kinesin family member 5B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane	Cytoplasm Microtubule Organizing Center Kinesin Complex Microtubule Membrane Endocytic Vesicle Vesicle Ciliary Rootlet Neuron Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Kinesin Binding Poly(A) RNA Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Microtubule-based Movement	Microtubule-based Movement Cytoplasm Organization Axon Guidance Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Synaptic Transmission, GABAergic Stress Granule Disassembly Regulation Of Membrane Potential Positive Regulation Of Potassium Ion Transport Cellular Protein Metabolic Process Vesicle Transport Along Microtubule Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways			Peptide hormone metabolism MHC class II antigen presentation Kinesins Insulin processing Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS			Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		14 interactors: AKT1 BNIP3 CDC42 CLEC7A EEF1D IKBKE KIF5B MEOX2 PLEKHA5 RAC1 RHOA RHOG SGTA SYNE4	23 interactors: APC CDC5L DTNB GSK3B KIF5A KLC3 KTN1 NCOA2 NDRG1 PRKAR2B RAPGEF2 RRBP1 SNAP23 SNAP25 SYBU TAX1BP1 VPS52 YWHAB YWHAG YWHAH YWHAQ YWHAZ ZBTB8A
Entrez ID		3895	3799
HPRD ID		02661	07214
Ensembl ID		ENSG00000126777	ENSG00000170759
Uniprot IDs		B4DZ88 Q5GGW3 Q86UP2	P33176 Q6P164
PDB IDs			1BG2 1MKJ 2P4N 4HNA
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Establishment Of Protein Localization To Plasma Membrane Axon Guidance Response To External Stimulus Positive Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of Protein Localization To Plasma Membrane Platelet Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Organization Axonogenesis Regulation Of Signaling T Cell Costimulation Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Epithelium Development Neuron Projection Morphogenesis Ephrin Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Cell Projection Organization Regulation Of Establishment Of Protein Localization Cell Activation Response To Wounding Intracellular Signal Transduction Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Regulation Of Cell Projection Assembly Regulation Of Cellular Component Organization Regulation Of Signal Transduction Regulation Of Protein Localization Defense Response Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Immune Response Establishment Or Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Immune System Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Organelle Organization	Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Regulation Of Protein Localization Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Protein Localization Positive Regulation Of Apoptotic Signaling Pathway Membrane Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Protein Transport Establishment Of Protein Localization Regulation Of Synaptic Plasticity Negative Regulation Of Dendrite Development Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Apoptotic Process Mast Cell Activation Programmed Cell Death Regulation Of Intracellular Transport Intracellular Signal Transduction Cell Death Cellular Localization Death Regulation Of Apoptotic Process Intracellular Transport Regulation Of Signaling Establishment Of Localization In Cell Regulation Of Cell Death Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synaptic Transmission Neurogenesis Positive Regulation Of Signal Transduction Histamine Secretion By Mast Cell Signaling Regulation Of Organelle Organization Nervous System Development Cell Communication Transport Regulation Of Cellular Component Organization Synaptic Vesicle Priming Histamine Secretion
Tagcloud ?		altering axon caudate circuits clustered cohorts conduct coordinate explained guidance influences influencing intergenic intracranial motivation neuropsychiatric putamen replicable rs945270 shaped stronger strongest subcortical variance variants vesicle volume volumes volumetric	actionable adenocarcinomas akt1 alk braf capture ccdc6 cd74 clip4 deemed driver fusions g719a genomic introns map2k1 nccn ngs nras pack pik3ca profiling rearranged ret ros1 socs5 targetable uniform v600e
Tagcloud (Difference) ?		altering axon caudate circuits clustered cohorts conduct coordinate explained guidance influences influencing intergenic intracranial motivation neuropsychiatric putamen replicable rs945270 shaped stronger strongest subcortical variance variants vesicle volume volumes volumetric	actionable adenocarcinomas akt1 alk braf capture ccdc6 cd74 clip4 deemed driver fusions g719a genomic introns map2k1 nccn ngs nras pack pik3ca profiling rearranged ret ros1 socs5 targetable uniform v600e
Tagcloud (Intersection) ?