KTN1 and EEF1D

Number of citations of the paper that reports this interaction (PMID 12773547)
8

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		KTN1	EEF1D
Gene Name		kinectin 1 (kinesin receptor)	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane	Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	Kinesin Binding Poly(A) RNA Binding	DNA Binding Translation Elongation Factor Activity Signal Transducer Activity Protein Binding Translation Factor Activity, Nucleic Acid Binding
	Biological Process	Microtubule-based Movement	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Signal Transduction Gene Expression Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Protein Metabolic Process
Pathways			Translation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AKT1 BNIP3 CDC42 CLEC7A EEF1D IKBKE KIF5B MEOX2 PLEKHA5 RAC1 RHOA RHOG SGTA SYNE4	33 interactors: ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS ERP27 FOS FRA10AC1 GARS HEXDC KARS KTN1 MAP1B NR2F1 POT1 PRKCA RELA RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 VARS
Entrez ID		3895	1936
HPRD ID		02661	00560
Ensembl ID		ENSG00000126777	ENSG00000104529
Uniprot IDs		B4DZ88 Q5GGW3 Q86UP2	B2RAR6 D3DWK1 P29692
PDB IDs
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Establishment Of Protein Localization To Plasma Membrane Axon Guidance Response To External Stimulus Positive Regulation Of Signal Transduction Blood Coagulation Hemostasis Regulation Of Protein Localization To Plasma Membrane Platelet Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Organization Axonogenesis Regulation Of Signaling T Cell Costimulation Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Epithelium Development Neuron Projection Morphogenesis Ephrin Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Cell Projection Organization Regulation Of Establishment Of Protein Localization Cell Activation Response To Wounding Intracellular Signal Transduction Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Regulation Of Cell Projection Assembly Regulation Of Cellular Component Organization Regulation Of Signal Transduction Regulation Of Protein Localization Defense Response Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Immune Response Establishment Or Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Immune System Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Organelle Organization	Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Protein Metabolic Process Movement Of Cell Or Subcellular Component Response To External Stimulus Negative Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Axonogenesis Regulation Of Telomere Maintenance Via Telomerase Axon Development Negative Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Cellular Metabolic Process Toll-like Receptor 10 Signaling Pathway Cell Differentiation Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Apoptotic Process Neuron Projection Morphogenesis Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death MyD88-independent Toll-like Receptor Signaling Pathway Diadenosine Tetraphosphate Biosynthetic Process Regulation Of Telomere Maintenance Toll-like Receptor 3 Signaling Pathway Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Viral Genome Replication Cell Morphogenesis Involved In Differentiation Negative Regulation Of Cell Death Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Schwann Cell Differentiation Neuron Projection Development Neurotrophin TRK Receptor Signaling Pathway Cell Projection Morphogenesis Nucleobase-containing Compound Metabolic Process Axon Guidance Chemotaxis Neurotrophin Signaling Pathway Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Histone H4 Acetylation
Tagcloud ?		altering axon caudate circuits clustered cohorts conduct coordinate explained guidance influences influencing intergenic intracranial motivation neuropsychiatric putamen replicable rs945270 shaped stronger strongest subcortical variance variants vesicle volume volumes volumetric
Tagcloud (Difference) ?		altering axon caudate circuits clustered cohorts conduct coordinate explained guidance influences influencing intergenic intracranial motivation neuropsychiatric putamen replicable rs945270 shaped stronger strongest subcortical variance variants vesicle volume volumes volumetric
Tagcloud (Intersection) ?